Xi'an Haixin Pharmaceutical Co., Ltd

Main research purpose: According to the relevant provisions of bioequivalence test, Aceclofenac Tablets (trade name: AIRTAL®, specification: 100 mg/tablet) produced by Almirall, S.A. was selected as the reference preparation, and the test preparation Aceclofenac Tablets (specification: 100 mg/tablet) produced by Xi'an Haixin Pharmaceutical Co., Ltd. was subjected to a human bioequivalence test after meal administration to compare whether the absorption rate and degree of the drug in the test preparation were within the acceptable range with the reference preparation, and to evaluate the bioequivalence of the two preparations under the condition of postprandial administration. Secondary research purpose: To observe the safety of oral administration of the test preparation Aceclofenac Tablets (specification: 100 mg/tablet) and the reference preparation Aceclofenac Tablets (trade name: AIRTAL®, specification: 100 mg/tablet) by healthy volunteers.

Main research purpose: According to the relevant provisions of bioequivalence test, Aceclofenac Tablets (trade name: AIRTAL®, specification: 100 mg/tablet) produced by Almirall, S.A. was selected as the reference preparation, and the test preparation Aceclofenac Tablets (specification: 100 mg/tablet) produced by Xi'an Haixin Pharmaceutical Co., Ltd. was used for fasting human bioequivalence test, to compare whether the absorption rate and degree of the drug in the test preparation were within the acceptable range with the reference preparation, and to evaluate the bioequivalence of the two preparations under fasting conditions. Secondary research purpose: To observe the safety of oral administration of the test preparation Aceclofenac Tablets (specification: 100 mg/tablet) and the reference preparation Aceclofenac Tablets (trade name: AIRTAL®, specification: 100 mg/tablet) by healthy volunteers.

Primary study objective To evaluate the absorption rate and extent of hydroxychloroquine sulfate tablets and Plaquenil® in healthy male and female subjects under fasting and postprandial conditions, and to evaluate whether the two preparations are bioequivalent. Secondary study objective To evaluate the safety of the test preparation hydroxychloroquine sulfate tablets and the reference preparation Plaquenil® in healthy Chinese subjects.