A newly developed pesticide, flupentiofenox, has a unique trifluoroethyl phenylsulfoxide structure, and it powerfully affects spider mites, including those with resistance to multiple commercial acaricides. To clarify the mode of action of flupentiofenox, we investigated its effect on mitochondrial energy generation. We observed that flupentiofenox decreased adenosine triphosphate (ATP) levels in two-spotted spider mites (Tetranychus urticae) at a practical dose. Flupentiofenox potently inhibited mitochondrial oxygen consumption under conditions of palmitoyl-carnitine or octanoic acid supply, but not under conditions of pyruvate supply. These results show that flupentiofenox inhibits the mitochondrial fatty acid metabolic pathway between the uptake of long-chain acylcarnitine or medium-chain fatty acid and the synthesis of acetyl-CoA by β-oxidation, resulting in suppressed mitochondrial energy generation. Our investigations have led us to conclude that flupentiofenox is a pesticide with a novel mode of action.

01 Feb 2024·Applied Entomology and Zoology

Inhibition of oenocytoid lysis of the common cutworm Spodoptera litura (Lepidoptera: Noctuidae) by carbon dioxide gas

Author: Kurihara, Yutaka ; Wago, Haruhisa

Abstract: Among the hemocytes of Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae), oenocytoids are lysed very quickly after hemolymph collection.We clarified that the lysis of oenocytoids can be greatly inhibited by collecting hemolymph under the introduction of carbon dioxide (CO₂) gas.Since nitrogen and helium gasses were ineffective in inhibiting oenocytoid lysis, it was concluded that CO₂ itself was necessary to inhibit lysis.Insect anesthetization with CO₂ gas before bleeding was not necessary to prevent oenocytoid lysis, but CO₂ gas was required at and after the time of bleeding.When the hemolymph was collected in a Petri dish under CO₂ gas and sealed, oenocytoids remained present without lysis even after an hour at 25 °C.Oenocytoids were not irreversibly fixed since lysis occurred when this hemolymph was exposed to air.When the hemolymph was collected in air, granulocytes adhered to the bottom surface of the Petri dish, and plasmatocytes spread out on the bottom surface.However, when collected under CO₂ gas, both types of hemocytes remained spherical, and few cells were observed to spread out on the bottom surface.Thus, it was suggested that oenocytoid lysis inhibition by CO₂ gas is associated with the suppression of defensive reactions to foreign materials by hemocytes.This hemolymph collection method can be easily performed without special pretreatment of the hemolymph.Accordingly, this method is considered to be advantageous for studying the possible role of oenocytoids associated with host defense mechanisms in insects.

20 Nov 2023·Journal of Pesticide Science

Characteristics biological activities of the novel acaricide flupentiofenox against phytophagous mites

Article

Author: Yoshimura, Shingo ; Mukawa, Shigeyuki

Flupentiofenox, which has a unique chemical structure, is a novel acaricide that has been developed by the Kumiai Chemical Industry Co., Ltd. Flupentiofenox exerted significant acaricidal activities against spider mites Tetranychus urticae and Panonychus citri at all developmental stages even at extremely low concentrations, as compared with its practical concentration (80 ppm) for use in mites and was effective against spider mite populations that are resistant to widely used commercial acaricides. These results suggested that flupentiofenox could be used effectively for the control and prevention of spider mite infestation. Additionally, flupentiofenox had a more rapid effect than acetyl CoA carboxylase inhibitors, but it had a relatively slower effect than mitochondrial electron transport inhibitors and glutamate-gated chloride channel modulators. Overall, flupentiofenox is assumed to have a new mode of action.

News (Medical) associated with Kumiai Chemical Industry Co., Ltd.

20 Sep 2022

·www.prnewswire.com

Curing Agent Market Size to Grow by USD 2.09 billion, New Product Launches to be Key Trend - Technavio

NEW YORK, Sept. 20, 2022 /PRNewswire/ -- New product launches are one of the major trends in the curing agent market. Successful new product launches increase the revenue flow of vendors and help expand their consumer base. This provides vendors a competitive edge over their rivals. For instance, in March 2020, Gabriel Performance Products, LLC announced the launch of new epoxy curing agents, namely VERSACURE RAC 9040 and RAC 9010UV. In December 2021, Evonik Industries AG launched Anquamine 469, a water-borne epoxy curing agent. Such launches will help established vendors to expand their market share in untapped consumer segments, which will further foster market growth. Continue Reading Technavio has announced its latest market research report titled Global Curing Agent Market 2022-2026 The curing agent market size is projected to grow by USD 2.09 billion from 2022 to 2026. In addition, the growth momentum of the market will accelerate at a CAGR of 7.11% during the forecast period, according to Technavio. Technavio provides a comprehensive report summary describing the market size and forecast along with research methodology. The FREE sample report is available in PDF format The increased demand for epoxy resin systems as a primer is driving the curing agent market growth. However, factors such as environmental regulations affecting market growth may challenge market growth. Curing Agent Market: Type Landscape By type, the market has been segmented into epoxy, polyurethane, silicone rubber, and others. The epoxy segment will generate maximum revenue in the curing agent market, owing to the wide range of architectural applications of epoxy resins. Curing Agent Market: Geographic Landscape In terms of geography, the market has been segmented into APAC, Europe, North America, South America, and the Middle East and Africa. APAC will present significant opportunities for market vendors due to factors such as steady economic expansion. Moreover, market growth in this region will be faster than the growth of the market in other regions. China, Japan, and India are the key markets for the curing agent market in APAC. Curing Agent Market: Key Vendor Analysis The curing agent market is fragmented, and the vendors are deploying organic and inorganic growth strategies to compete in the market. Aditya Birla Management Corp. Pvt. Ltd., Albemarle Corp., Atul Ltd., BASF SE, Campbell Plastics Ltd., Cardolite Corp., Cargill Inc., Evonik Industries AG, Hexion Inc., Huntsman International LLC, KUKDO Chemical Kunshan Co. Ltd., Kumiai Chemical Industry Co. Ltd., LEUNA Harze GmbH, Mitsubishi Chemical Corp., Nan Ya Plastics Corp., Olin Corp., RPM International Inc., Shandong Deyuan Epoxy Resin Co. Ltd., Vijai Poly Products Pvt. Ltd., Yunteh Industries, among others, are some of the key vendors operating in the market. Technavio's reports provide key strategic initiatives used by vendors, along with key news and the latest developments. View our FREE PDF Sample Report Now Curing Agent Market: What our Reports Offer Market share assessments for the regional and country-level segments Strategic recommendations for the new entrants Covers market data for 2021, 2022, until 2026 Market trends (drivers, opportunities, threats, challenges, investment opportunities, and recommendations) Strategic recommendations in key business segments based on the market estimations Competitive landscaping mapping the key common trends Company profiling with detailed strategies, financials, and recent developments Supply chain trends mapping the latest technological advancements Get lifetime access to our Technavio Insights! Subscribe to our "Basic Plan" billed annually at USD 5000 Related Reports Cell Culture Media and Reagents Market by End-user and Geography - Forecast and Analysis 2021-2025: The cell culture media and reagents market share is expected to increase by USD 2.26 billion from 2020 to 2025. Erythropoietin Stimulating Agents Market by Type and Geography - Forecast and Analysis 2022-2026: The erythropoietin stimulating agents market share is expected to increase by USD 4.74 billion from 2021 to 2026. Browse Health Care Market Reports Table of Contents 1 Executive Summary 1.1 Market overview Exhibit 01: Executive Summary – Chart on Market Overview Exhibit 02: Executive Summary – Data Table on Market Overview Exhibit 03: Executive Summary – Chart on Global Market Characteristics Exhibit 04: Executive Summary – Chart on Market by Geography Exhibit 05: Executive Summary – Chart on Market Segmentation by Type Exhibit 06: Executive Summary – Chart on Incremental Growth Exhibit 07: Executive Summary – Data Table on Incremental Growth Exhibit 08: Executive Summary – Chart on Vendor Market Positioning 2 Market Landscape 2.1 Market ecosystem Exhibit 09: Parent market Exhibit 10: Market Characteristics 3 Market Sizing 3.1 Market definition Exhibit 11: Offerings of vendors included in the market definition 3.2 Market segment analysis Exhibit 12: Market segments 3.3 Market size 2021 3.4 Market outlook: Forecast for 2021-2026 Exhibit 13: Chart on Global - Market size and forecast 2021-2026 ($ million) Exhibit 14: Data Table on Global - Market size and forecast 2021-2026 ($ million) Exhibit 15: Chart on Global Market: Year-over-year growth 2021-2026 (%) Exhibit 16: Data Table on Global Market: Year-over-year growth 2021-2026 (%) 4 Five Forces Analysis 4.1 Five forces summary Exhibit 17: Five forces analysis - Comparison between 2021 and 2026 4.2 Bargaining power of buyers Exhibit 18: Chart on Bargaining power of buyers – Impact of key factors 2021 and 2026 4.3 Bargaining power of suppliers Exhibit 19: Bargaining power of suppliers – Impact of key factors in 2021 and 2026 4.4 Threat of new entrants Exhibit 20: Threat of new entrants – Impact of key factors in 2021 and 2026 4.5 Threat of substitutes Exhibit 21: Threat of substitutes – Impact of key factors in 2021 and 2026 4.6 Threat of rivalry Exhibit 22: Threat of rivalry – Impact of key factors in 2021 and 2026 4.7 Market condition Exhibit 23: Chart on Market condition - Five forces 2021 and 2026 5 Market Segmentation by Type 5.1 Market segments Exhibit 24: Chart on Type - Market share 2021-2026 (%) Exhibit 25: Data Table on Type - Market share 2021-2026 (%) 5.2 Comparison by Type Exhibit 26: Chart on Comparison by Type Exhibit 27: Data Table on Comparison by Type 5.3 Epoxy - Market size and forecast 2021-2026 Exhibit 28: Chart on Epoxy - Market size and forecast 2021-2026 ($ million) Exhibit 29: Data Table on Epoxy - Market size and forecast 2021-2026 ($ million) Exhibit 30: Chart on Epoxy - Year-over-year growth 2021-2026 (%) Exhibit 31: Data Table on Epoxy - Year-over-year growth 2021-2026 (%) 5.4 Polyurethane - Market size and forecast 2021-2026 Exhibit 32: Chart on Polyurethane - Market size and forecast 2021-2026 ($ million) Exhibit 33: Data Table on Polyurethane - Market size and forecast 2021-2026 ($ million) Exhibit 34: Chart on Polyurethane - Year-over-year growth 2021-2026 (%) Exhibit 35: Data Table on Polyurethane - Year-over-year growth 2021-2026 (%) 5.5 Silicone Rubber - Market size and forecast 2021-2026 Exhibit 36: Chart on Silicone Rubber - Market size and forecast 2021-2026 ($ million) Exhibit 37: Data Table on Silicone Rubber - Market size and forecast 2021-2026 ($ million) Exhibit 38: Chart on Silicone Rubber - Year-over-year growth 2021-2026 (%) Exhibit 39: Data Table on Silicone Rubber - Year-over-year growth 2021-2026 (%) 5.6 Others - Market size and forecast 2021-2026 Exhibit 40: Chart on Others - Market size and forecast 2021-2026 ($ million) Exhibit 41: Data Table on Others - Market size and forecast 2021-2026 ($ million) Exhibit 42: Chart on Others - Year-over-year growth 2021-2026 (%) Exhibit 43: Data Table on Others - Year-over-year growth 2021-2026 (%) 5.7 Market opportunity by Type Exhibit 44: Market opportunity by Type ($ million) 6 Customer Landscape 6.1 Customer landscape overview Exhibit 45: Analysis of price sensitivity, lifecycle, customer purchase basket, adoption rates, and purchase criteria 7 Geographic Landscape 7.1 Geographic segmentation Exhibit 46: Chart on Market share by geography 2021-2026 (%) Exhibit 47: Data Table on Market share by geography 2021-2026 (%) 7.2 Geographic comparison Exhibit 48: Chart on Geographic comparison Exhibit 49: Data Table on Geographic comparison 7.3 APAC - Market size and forecast 2021-2026 Exhibit 50: Chart on APAC - Market size and forecast 2021-2026 ($ million) Exhibit 51: Data Table on APAC - Market size and forecast 2021-2026 ($ million) Exhibit 52: Chart on APAC - Year-over-year growth 2021-2026 (%) Exhibit 53: Data Table on APAC - Year-over-year growth 2021-2026 (%) 7.4 Europe - Market size and forecast 2021-2026 Exhibit 54: Chart on Europe - Market size and forecast 2021-2026 ($ million) Exhibit 55: Data Table on Europe - Market size and forecast 2021-2026 ($ million) Exhibit 56: Chart on Europe - Year-over-year growth 2021-2026 (%) Exhibit 57: Data Table on Europe - Year-over-year growth 2021-2026 (%) 7.5 North America - Market size and forecast 2021-2026 Exhibit 58: Chart on North America - Market size and forecast 2021-2026 ($ million) Exhibit 59: Data Table on North America - Market size and forecast 2021-2026 ($ million) Exhibit 60: Chart on North America - Year-over-year growth 2021-2026 (%) Exhibit 61: Data Table on North America - Year-over-year growth 2021-2026 (%) 7.6 South America - Market size and forecast 2021-2026 Exhibit 62: Chart on South America - Market size and forecast 2021-2026 ($ million) Exhibit 63: Data Table on South America - Market size and forecast 2021-2026 ($ million) Exhibit 64: Chart on South America - Year-over-year growth 2021-2026 (%) Exhibit 65: Data Table on South America - Year-over-year growth 2021-2026 (%) 7.7 Middle East and Africa - Market size and forecast 2021-2026 Exhibit 66: Chart on Middle East and Africa - Market size and forecast 2021-2026 ($ million) Exhibit 67: Data Table on Middle East and Africa - Market size and forecast 2021-2026 ($ million) Exhibit 68: Chart on Middle East and Africa - Year-over-year growth 2021-2026 (%) Exhibit 69: Data Table on Middle East and Africa - Year-over-year growth 2021-2026 (%) 7.8 US - Market size and forecast 2021-2026 Exhibit 70: Chart on US - Market size and forecast 2021-2026 ($ million) Exhibit 71: Data Table on US - Market size and forecast 2021-2026 ($ million) Exhibit 72: Chart on US - Year-over-year growth 2021-2026 (%) Exhibit 73: Data Table on US - Year-over-year growth 2021-2026 (%) 7.9 China - Market size and forecast 2021-2026 Exhibit 74: Chart on China - Market size and forecast 2021-2026 ($ million) Exhibit 75: Data Table on China - Market size and forecast 2021-2026 ($ million) Exhibit 76: Chart on China - Year-over-year growth 2021-2026 (%) Exhibit 77: Data Table on China - Year-over-year growth 2021-2026 (%) 7.10 Japan - Market size and forecast 2021-2026 Exhibit 78: Chart on Japan - Market size and forecast 2021-2026 ($ million) Exhibit 79: Data Table on Japan - Market size and forecast 2021-2026 ($ million) Exhibit 80: Chart on Japan - Year-over-year growth 2021-2026 (%) Exhibit 81: Data Table on Japan - Year-over-year growth 2021-2026 (%) 7.11 India - Market size and forecast 2021-2026 Exhibit 82: Chart on India - Market size and forecast 2021-2026 ($ million) Exhibit 83: Data Table on India - Market size and forecast 2021-2026 ($ million) Exhibit 84: Chart on India - Year-over-year growth 2021-2026 (%) Exhibit 85: Data Table on India - Year-over-year growth 2021-2026 (%) 7.12 Germany - Market size and forecast 2021-2026 Exhibit 86: Chart on Germany - Market size and forecast 2021-2026 ($ million) Exhibit 87: Data Table on Germany - Market size and forecast 2021-2026 ($ million) Exhibit 88: Chart on Germany - Year-over-year growth 2021-2026 (%) Exhibit 89: Data Table on Germany - Year-over-year growth 2021-2026 (%) 7.13 Market opportunity by geography Exhibit 90: Market opportunity by geography ($ million) 8 Drivers, Challenges, and Trends 8.1 Market drivers 8.2 Market challenges 8.3 Impact of drivers and challenges Exhibit 91: Impact of drivers and challenges in 2021 and 2026 8.4 Market trends 9 Vendor Landscape 9.1 Overview 9.2 Vendor landscape Exhibit 92: Overview on Criticality of inputs and Factors of differentiation 9.3 Landscape disruption Exhibit 93: Overview on factors of disruption 9.4 Industry risks Exhibit 94: Impact of key risks on business 10 Vendor Analysis 10.1 Vendors covered Exhibit 95: Vendors covered 10.2 Market positioning of vendors Exhibit 96: Matrix on vendor position and classification 10.3 Aditya Birla Management Corp. Pvt. Ltd. Exhibit 97: Aditya Birla Management Corp. Pvt. Ltd. - Overview Exhibit 98: Aditya Birla Management Corp. Pvt. Ltd. - Product / Service Exhibit 99: Aditya Birla Management Corp. Pvt. Ltd. - Key offerings 10.4 Albemarle Corp. Exhibit 100: Albemarle Corp. - Overview Exhibit 101: Albemarle Corp. - Business segments Exhibit 102: Albemarle Corp. - Key news Exhibit 103: Albemarle Corp. - Key offerings Exhibit 104: Albemarle Corp. - Segment focus 10.5 BASF SE Exhibit 105: BASF SE - Overview Exhibit 106: BASF SE - Business segments Exhibit 107: BASF SE - Key news Exhibit 108: BASF SE - Key offerings Exhibit 109: BASF SE - Segment focus 10.6 Cardolite Corp. Exhibit 110: Cardolite Corp. - Overview Exhibit 111: Cardolite Corp. - Product / Service Exhibit 112: Cardolite Corp. - Key offerings 10.7 Evonik Industries AG Exhibit 113: Evonik Industries AG - Overview Exhibit 114: Evonik Industries AG - Business segments Exhibit 115: Evonik Industries AG - Key news Exhibit 116: Evonik Industries AG - Key offerings Exhibit 117: Evonik Industries AG - Segment focus 10.8 Hexion Inc. Exhibit 118: Hexion Inc. - Overview Exhibit 119: Hexion Inc. - Business segments Exhibit 120: Hexion Inc. - Key news Exhibit 121: Hexion Inc. - Key offerings Exhibit 122: Hexion Inc. - Segment focus 10.9 Huntsman International LLC Exhibit 123: Huntsman International LLC - Overview Exhibit 124: Huntsman International LLC - Business segments Exhibit 125: Huntsman International LLC - Key news Exhibit 126: Huntsman International LLC - Key offerings Exhibit 127: Huntsman International LLC - Segment focus 10.10 KUKDO Chemical Kunshan Co. Ltd. Exhibit 128: KUKDO Chemical Kunshan Co. Ltd. - Overview Exhibit 129: KUKDO Chemical Kunshan Co. Ltd. - Product / Service Exhibit 130: KUKDO Chemical Kunshan Co. Ltd. - Key offerings 10.11 Mitsubishi Chemical Corp. Exhibit 131: Mitsubishi Chemical Corp. - Overview Exhibit 132: Mitsubishi Chemical Corp. - Business segments Exhibit 133: Mitsubishi Chemical Corp. - Key news Exhibit 134: Mitsubishi Chemical Corp. - Key offerings Exhibit 135: Mitsubishi Chemical Corp. - Segment focus 10.12 Olin Corp. Exhibit 136: Olin Corp. - Overview Exhibit 137: Olin Corp. - Business segments Exhibit 138: Olin Corp. - Key offerings Exhibit 139: Olin Corp. - Segment focus 11 Appendix 11.1 Scope of the report 11.2 Inclusions and exclusions checklist Exhibit 140: Inclusions checklist Exhibit 141: Exclusions checklist 11.3 Currency conversion rates for US$ Exhibit 142: Currency conversion rates for US$ 11.4 Research methodology Exhibit 143: Research methodology Exhibit 144: Validation techniques employed for market sizing Exhibit 145: Information sources 11.5 List of abbreviations Exhibit 146: List of abbreviations About Us Technavio is a leading global technology research and advisory company. Their research and analysis focuses on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios. Contact Technavio Research Jesse Maida Media & Marketing Executive US: +1 844 364 1100 UK: +44 203 893 3200 Email: [email protected] Website: SOURCE Technavio

100 Deals associated with Kumiai Chemical Industry Co., Ltd.

100 Translational Medicine associated with Kumiai Chemical Industry Co., Ltd.

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IKP-104	Neoplasms More	Discontinued
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