Shandong Yidu Biotechnology Co., Ltd.

Primary objective: (1) To evaluate the batch-to-batch consistency of immunogenicity of three consecutive production batches of freeze-dried human rabies vaccine (Vero cells) after administration with a five-dose (1-1-1-1-1) immunization schedule; Secondary objective: (1) To evaluate the safety of freeze-dried human rabies vaccine (Vero cells) administered in healthy people with a five-dose (1-1-1-1-1) immunization schedule.

Compared with similar marketed vaccines, the immunogenicity and safety of a 5-dose immunization schedule of freeze-dried human rabies vaccine were evaluated; compared with a 5-dose immunization schedule, the immunogenicity and safety of a 4-dose immunization schedule were evaluated.