A Comparative Study on the Efficacy of Tamsulosin, Solifenacin and Mirabegron in Alleviating Ureteral Stent-related Symptoms: a Randomized Controlled Trial

A comparative study on the efficacy of Tamsulosin, Solifenacin and Mirabegron in alleviating ureteral stent-related symptoms: a randomized controlled trial.

Start Date01 Apr 2025

Sponsor / Collaborator

Bir Hospital

NCT06830902

/ Not yet recruitingNot ApplicableIIT

Comparison of Stent Related Symptoms Between Regular Double J Stent Versus Comfi J Stent: A Single Blinded Randomized Controlled Trial

A prospective, single-blinded, randomized controlled trial conducted at a single center to compare stent related symptoms between two different stents using Ureteral Stent Symptom Questionnaire (USSQ) scores , Visual Analog Scale (VAS) pain scores.

Start Date15 Feb 2025

Sponsor / Collaborator

Bir Hospital

100 Clinical Results associated with Bir Hospital

0 Patents (Medical) associated with Bir Hospital

565

Literatures (Medical) associated with Bir Hospital

01 Apr 2025·Annals of Medicine & Surgery

Critical anatomical variants in preoperative computed tomography of paranasal sinuses in a tertiary care center: a cross-sectional study

Article

Author: Dahal, Prajwal ; Adhikari, Govinda ; Maharjan, Santosh ; Upadhyaya, Rudra Prasad ; Dhakal, Natasha ; Parajuli, Sabina ; Ghimire, Samjhana

Background:Certain anatomical variants of the paranasal sinuses (PNS) predispose to injury of surrounding critical structures during functional endoscopic sinus surgery (FESS) and the occurrence of common pathologies like sinusitis. However, they are often not reported in preoperative computed tomography (CT).Methods:The CT scan of PNS and head of 360 adults (age > 13 years) were retrospectively evaluated for variants of cribriform plate, olfactory fossa, lamina papyracea, uncinate process, sphenoid pneumatization, and anterior ethmoid artery by 4 radiologists with experience of 3 to 6 years. The prevalence of each variant was obtained. Chi-squared and independent sample t-tests were used to analyze relationships between variables, with significance set at P < .05.Results:The prevalence of Keros Type 1, Type 2, and Type 3 olfactory fossa was 24.4%, 66.9%, and 8.6%, respectively, in the right side and 20.6%, 69.2%, and 10.3%, respectively, in the left side. Mean depth of right and left olfactory fossa was 4.9 mm (±1.9) and 5.2 mm (± 1.8), respectively. Dehiscence/remote fracture of anterior skull base was observed in 1.9% cases. Dehiscence/remote fracture of lamina papyracea was present in 2.8% cases. Haller cells were observed in 13.9%. Conchal, presellar, incomplete sellar, and complete sellar pattern of pneumatization of sphenoid sinus had prevalences of 2.5%, 6.4%, 26.7%, and 64.4%, respectively. The prevalence of dehiscence of carotid canal in sphenoid sinus was 7.2%. The prevalence of bony septa insertion into carotid canal was 37.8%. The prevalence of supraorbital pneumatization was 51.4%. The prevalence of agger nasi cell and pneumatization of crista galli were 82.2% and 16.7%, respectively.Conclusion:Preoperative CT provides an opportunity to look for critical structures in relation to the PNS. Radiologists should report these findings to prevent potential complications during FESS.

01 Mar 2025·Radiology Case Reports

Incidental left paraaortic mass in a patient with gall bladder adenocarcinoma: A diagnostic challenge

Article

Author: Dahal, Prajwal ; Bhatta, Manali ; Paudel, Sharma ; Shrestha, Santosh ; Tamang, Ongden Yonjen ; Parajuli, Sabina

Incidental adrenal masses are frequently detected due to the extensive use of cross-sectional imaging, with about 3% to 7% of adults estimated to have them. Paragangliomas and pheochromocytomas (PPGL), rare tumors originating from paraganglia tissues, including the adrenal medulla, continue to be imaging mimics, necessitating a multimodal approach for accurate diagnosis. We report a case of 72-years male presenting with intermittent pain abdomen for the past 1 year. Preliminary imaging by ultrasound revealed a suspicious gall bladder polypoidal lesion along with choledochal cyst for which further characterization was done with both CT and MRI. On imaging besides defining the findings seen in USG, we encountered a large heterogeneously enhancing possible left adrenal incidentaloma. A homogeneously hyper enhancing lesion along the paraganglia distribution, with no evidence of washout and a high T2 signal, is a hallmark imaging characteristic of pheochromocytomas and paragangliomas. However, around 35% of atypical lesions, often altered by degenerative changes, deviate from these typical imaging patterns, presenting a diagnostic dilemma. Histopathological analysis, including immunohistochemistry, biochemical testing, and functional imaging, can offer valuable insights to help diagnose and aid in predicting prognosis.

01 Dec 2024·Radiology Case Reports

Navigating diagnostic challenges in xanthogranulomatous cholecystitis: A case report

Article

Author: Dahal, Prajwal ; Dhakal, Natasha ; Tamang, Ongden Yonjen ; Adhikari, Govinda ; Parajuli, Sabina ; Maharjan, Santosh ; Upadhyaya, Rudra Prasad

Xanthogranulomatous cholecystitis (XGC) presents a diagnostic challenge due to its rarity and varied clinical manifestations and nonspecific radiological findings. We here describe a 67-year-old man with right hypochondriac pain, where imaging revealed irregular thickening of the gallbladder wall, prompting consideration of various differential diagnoses including gallbladder malignancy, adenomyomatosis, and complicated cholecystitis. With inconclusive lab results, cholecystectomy with potential extended hepatectomy was advised. Intraoperatively, an inflamed gallbladder was observed. Histopathological examination confirmed XGC, stressing histological verification. Complete cholecystectomy is standard, with partial resection an option. Our case details the complexity in diagnosis and management of XGC.

100 Deals associated with Bir Hospital

100 Translational Medicine associated with Bir Hospital

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