[Translation] A phase I dose-escalation and dose-expansion study of the safety, tolerability, and efficacy of BST02 injection in the treatment of advanced hepatocellular carcinoma
主要目的:评估BST02注射液治疗晚期肝癌受试者的安全性和耐受性。
次要目的:评估BST02注射液治疗晚期肝癌受试者的初步有效性;评估BST02注射液的药代动力学(Pharmacokinetics,PK)特征。
探索性目的:探索BST02注射液的药效动力学(Pharmacodynamics,PD)特征。
[Translation] Primary objective: To evaluate the safety and tolerability of BST02 injection in the treatment of subjects with advanced liver cancer.
Secondary objective: To evaluate the preliminary efficacy of BST02 injection in the treatment of subjects with advanced liver cancer; to evaluate the pharmacokinetic (PK) characteristics of BST02 injection.
Exploratory objective: To explore the pharmacodynamic (PD) characteristics of BST02 injection.