Nanjing Heron Pharmaceutical Co.,Ltd.

Main study objectives: To use the tetraenylquinone soft capsules (specification: 15 mg) produced by Nanjing Hairong Pharmaceutical Co., Ltd. as the test preparation and the tetraenylquinone soft capsules (trade name: Gulikang, specification: 15 mg) produced by Eisai Co., Ltd. as the reference preparation, to investigate the pharmacokinetic parameters and relative bioavailability of the two preparations after single administration under fasting conditions, and to evaluate whether the two preparations are bioequivalent. Secondary study objectives: To evaluate the safety of the test preparation and the reference preparation in healthy participants.

Main research objectives: Pemabet tablets (specification: 0.1 mg) produced by Nanjing Hairong Pharmaceutical Co., Ltd. was used as the test preparation, and Pemabet tablets (specification: 0.1 mg) produced by the certified manufacturer Kowa Co., Ltd. was used as the reference preparation. The pharmacokinetic parameters and relative bioavailability of the two preparations after single administration in the fasting and postprandial states were investigated to evaluate whether the two preparations were bioequivalent. Secondary study objectives: To evaluate the safety of test and reference products in healthy research participants.

Main study objectives: Using ketorolac tromethamine tablets (specification: 10 mg) produced by Nanjing Hairong Pharmaceutical Co., Ltd. as the test preparation and ketorolac tromethamine tablets (specification: 10 mg) produced by Teva Pharmaceuticals USA, Inc. as the reference preparation, the pharmacokinetic parameters and relative bioavailability of the two preparations after single administration under fasting state were investigated to evaluate whether the two preparations are bioequivalent. Secondary study objectives: Evaluate the safety of the test preparation and the reference preparation in healthy subjects.