Shandong Daoqi Biomedical Technology Co., Ltd.

Primary objective: To study the pharmacokinetic behavior of the test formulation of baclofen oral solution (specification: 5 mg/5 mL, produced by Zhongfu Pharmaceutical Co., Ltd., provided by Shandong Daoqi Biopharmaceutical Technology Co., Ltd.) and the reference formulation of baclofen oral solution (Lioresal®, specification: 5 mg/5 mL, licensed by Novartis Pharmaceuticals UK Limited, provided by Shandong Daoqi Biopharmaceutical Technology Co., Ltd.) in healthy Chinese subjects after single oral administration on an empty stomach and after a meal, and to evaluate the bioequivalence of the two formulations after oral administration on an empty stomach and after a meal. Secondary objective: To evaluate the safety and taste of the test formulation (T) and the reference formulation (R) of baclofen oral solution in healthy Chinese subjects after single oral administration on an empty stomach and after a meal.