Delving into the Latest Updates on Innophore GmbH with Synapse

Overview

Tags

Respiratory Diseases

Infectious Diseases

Recombinant protein

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Infectious Diseases	1

Top 5 Drug Type	Count

Recombinant protein	1

Top 5 Target	Count

ACE2(Angiotensin-converting enzyme 2)	1

AbstractRecent advances in bioeconomy allow a holistic view of existing and new process chains and enable novel production routines continuously advanced by academia and industry. All this progress benefits from a growing number of prediction tools that have found their way into the field. For example, automated genome annotations, tools for building model structures of proteins, and structural protein prediction methods such as AlphaFold2TM or RoseTTAFold have gained popularity in recent years. Recently, it has become apparent that more and more AI‐based tools are being developed and used for biocatalysis and biotechnology. This is an excellent opportunity for academia and industry to accelerate advancements in the field further. Biotechnology, as a rapidly growing interdisciplinary field, stands to benefit greatly from these developments.

07 Jul 2023·ACS Catalysis

A Career in Catalysis: Bernhard Hauer

Author: Syrén, Per-Olof ; Aberle, Benjamin ; Weissenborn, Martin J. ; Breuer, Michael ; Schneider, Andreas ; Nestl, Bettina M. ; Nebel, Bernd A. ; Hammer, Stephan C.

01 Feb 2021·iScienceQ2 · CROSS-FIELD

A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening

Q2 · CROSS-FIELD

ArticleOA

Author: Herce, Henry D ; Namchuk, Mark N ; Moroz, Yurii ; Lewis, Noam ; Gruber, Christian ; Yust, Ryan ; Chuprina, Alexander ; Pandita, Shreya ; Kinney, Jamie ; Fischer, Patrick D ; Luxenburg, Roni ; Durmaz, Vedat ; Tesseyre, Guilhem ; Padmanabha Das, Krishna M ; Yavnyuk, Irina ; Dziuba, Igor ; Patten, J J ; Hutcheson, Colin ; Calderaio, Anthony ; Yaffe, Erez ; Rose, Alexander ; Plekhova, Alla ; Arthanari, Haribabu ; Halazonetis, Thanos D ; Radchenko, Dmytro ; Gechev, Minko ; Davey, Robert A ; Cespugli, Marco ; Fackeldey, Konstantin ; Tarkhanova, Olga ; Payne, Dave ; Leigh, Kendra E ; Shnapir, Alec ; Näär, Anders M ; Wang, Zi-Fu ; Gorgulla, Christoph ; Wagner, Gerhard

The unparalleled global effort to combat the continuing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic over the last year has resulted in promising prophylactic measures. However, a need still exists for cheap, effective therapeutics, and targeting multiple points in the viral life cycle could help tackle the current, as well as future, coronaviruses. Here, we leverage our recently developed, ultra-large-scale in silico screening platform, VirtualFlow, to search for inhibitors that target SARS-CoV-2. In this unprecedented structure-based virtual campaign, we screened roughly 1 billion molecules against each of 40 different target sites on 17 different potential viral and host targets. In addition to targeting the active sites of viral enzymes, we also targeted critical auxiliary sites such as functionally important protein-protein interactions.

100 Deals associated with Innophore GmbH

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100 Translational Medicine associated with Innophore GmbH

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Pipeline

Pipeline Snapshot as of 17 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Preclinical

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