The high comorbidity of mental health issues and meth use in women worsens both their mental health and meth use outcomes. The study team proposes to evaluate the potential of Friendship Bench to be used as a low-threshold, task-shifting mental health intervention among women who use methamphetamine in Vietnam - a lower-middle-income country. The study will provide preliminary data for a R01 trial testing the effectiveness Friendship Bench to improve mental health and methamphetamine use outcomes among women who use methamphetamine in Vietnam.

Start Date01 Sep 2025

Sponsor / Collaborator

Hanoi Medical University

[+3]

NCT06858670

/ RecruitingNot ApplicableIIT

Effectiveness of Auxiliary Segmental Lingual Appliances in Leveling the Curve of Wilson at Second Molars

This study aims to evaluate the effectiveness of auxiliary segmental lingual appliances in leveling the Curve of Wilson at the second molars in patients undergoing labial fixed orthodontic treatment. Patients exhibiting an excessive (deep) Curve of Wilson at the second molar bilaterally (meaning lingually inclined mandibular second molar) will be recruited.. Using a split-mouth design, one side will receive the intervention (auxiliary segmental lingual appliances), while the other side will serve as the control. The variables measured include the Curve of Wilson at the second and first molars, and the distance from the mesiolingual and distolingual cusps of the second molar to the occlusal plane of the first molar. Measurements will be taken on digital impressions at baseline (T0), after leveling with a stainless steel labial archwire (T1), and three months after applying the auxiliary segmental lingual appliances. The effectiveness will be assessed by comparing the two groups.

Start Date01 Mar 2025

Sponsor / Collaborator

Hanoi Medical University

NCT06615427

/ RecruitingNot ApplicableIIT

Delivered and Assessed FiO2 in Neonates with Respiratory Distress and Treated with Bubble-CPAP At a Neonatal Intensive Care Unit in Hanoi, Vietnam

Continuous positive airway pressure (CPAP) is the mainstay of treatment recommended for preterm infants with respiratory distress syndrome in all resource contexts. Many of the available bubble CPAP machines in low- and middle-income contexts mix flows of air and oxygen. These are adjusted by two separate rotameters (flowmeters) and estimate FiO2 delivery. Medical decisions regarding interventions to sick neonates such as need for intubation or surfactant administration are in large part dependant on a reliable estimation of FiO2-delivery. The aim of this study is to evaluate the accuracy of FiO2 delivered by bubble-CPAP machines with separate oxygen and air rotameters in patients at a neonatal intensive care unit (NICU) in Hanoi.

Start Date28 Sep 2024

Sponsor / Collaborator

Karolinska Institutet

[+1]

100 Clinical Results associated with Hanoi Medical University

0 Patents (Medical) associated with Hanoi Medical University

3,123

Literatures (Medical) associated with Hanoi Medical University

31 Dec 2025·Global Health Action

Prevalence and risk factors of gestational diabetes mellitus among pregnant women in northern Vietnam: a cross-sectional study

Article

Author: Vinter, Christina A. ; Bygbjerg, Ib Christian ; Nguyen, Thi Ai ; Nguyen, Dang Kien ; Søndergaard, Jens ; Søndergaard Linde, Ditte ; Thi Dang, Ngoc-Anh ; Rasch, Vibeke ; Meyrowitsch, Dan W. ; Quang Nguyen, Bay ; Gammeltoft, Tine M. ; Duc Nguyen, Thanh ; Le, Hieu Minh ; Nguyen, Xuan Bai

BACKGROUNDGestational diabetes mellitus (GDM) increases adverse neonatal and maternal outcomes. Understanding the prevalence and risk factors of GDM is necessary to plan health care interventions and policy.OBJECTIVETo determine the prevalence and risk factors of GDM in Thai Binh, Vietnam.METHODSA cross-sectional study was conducted in two health facilities in Thai Binh, Vietnam, with the participation of 1,106 pregnant women. Women were recruited at their first antenatal care visit where face-to-face interviews about socioeconomic and reproductive factors were performed. A 2-hour 75 g oral glucose tolerance test was conducted at 24-28 weeks of gestation. GDM was diagnosed according to the World Health Organization 2013 criteria. Logistic regression analyses were used to assess the factors associated with GDM.RESULTSThe prevalence rate of GDM was 27.1%. Multivariate logistic regression analysis showed maternal age from 25 to 34 (adjusted OR 2.0; 95%CI 1.3-2.9), maternal age ≥ 35 (adjusted OR 3.0; 95%CI 1.7-5.4), pregestational body mass index ≥ 23 (adjusted OR 1.6; 95%CI 1.1-2.3), family history of diabetes (adjusted OR 1.9; 95%CI 1.3-2.9), fertility treatment (adjusted OR 2.3; 95%CI 1.3-3.8), and previous GDM (adjusted OR 3.1; 95%CI 1.4-6.9) were associated with increased odds of GDM.CONCLUSIONSMore than one-fourth of pregnant women in Thai Binh, Vietnam, may have GDM. Advanced maternal age, high pregestational body mass index, family history of diabetes, and previous GDM were associated with increased risk of GDM. Additionally, fertility treatment appears to be strongly associated with an increased risk of GDM.

31 Dec 2025·Expert Review of Vaccines

Safety profile of self-amplifying mRNA SARS-CoV-2 vaccine ARCT-154 in adults: a pooled phase 1/2/3 randomized clinical study

Article

Author: Nnah, Ekpeno ; Baccarini, Carmen ; Nguyen, Van Thu ; Parker, Suezanne ; Luong, Quang Chan ; Walson, Judd L ; Van Chu, Men ; Ta, Van Thanh ; Ho, Nhan Thi ; Hawkes, Alia ; Pham, Hung Ngoc ; Pham, Ha Thai ; Trinh, Quang Vinh ; Nguyen, Toan Trong ; Verhoeven, Carole ; Thi Le Tran, Ly ; Nguyen, Xuan-Hung ; Nguyen, Anh Ngoc ; Van Nguyen, Thang ; Nguyen, Thuong Vu ; Ngoc Dang, Mai Thi ; Le, Vy Thi Tuong ; Dao, Giang Duc ; Van Pham, Anh Thi ; Smolenov, Igor

BACKGROUNDPublic health concerns due to ongoing emergence of SARS-CoV-2 variants necessitates further development of improved COVID-19 vaccines. One major innovation are self-amplifying mRNA vaccines, such as ARCT-154 (Arcturus Therapeutics, Inc.), which induces superior immunogenicity compared with conventional mRNA in terms of magnitude, breadth and persistence of neutralizing antibodies.RESEARCH DESIGN AND METHODSIn a pivotal placebo-controlled trial in Vietnam combining phase 1, 2 and 3 cohorts, over 17,000 adults received at least one dose of ARCT-154. Here, we report the safety and reactogenicity observations made.RESULTSARCT-154 elicited more local reactions than the saline placebo, most reports of injection site pain were mild/moderate with only a few reporting severe pain. Most frequent solicited adverse events were fatigue, myalgia, headache, arthralgia and chills. Solicited local and systemic reactogenicity resolved within 7 days. Long-term follow-up has not revealed any safety concerns, with no reports of myocarditis or pericarditis. Acceptable tolerability of ARCT-154 was also observed in older participants and in those liable to severe consequences of COVID-19 due to underlying medical conditions. No serious consequences occurred in several pregnancies reported after vaccination, with normal outcomes when followed to term.CONCLUSIONSData from this large trial suggest that ARCT-154 is safe and well tolerated.

31 Dec 2025·The Aging Male

Association of testicular histopathology with sperm retrieval success rates in men with idiopathic non-obstructive azoospermia

Article

Author: Dinh Huu, Viet ; Nguyen Cao, Thang ; Nguyen Hoai, Bac ; A. Jannini, Emmanuele

INTRODUCTIONInfertility is a major public health issue, with male factors alone contributing to 20-30% of cases. Non-obstructive azoospermia (NOA) is the most severe form, and although techniques like microdissection testicular sperm extraction (mTESE) offer hope, it remains challenging due to its uncertain causes. This study investigates the correlation between testicular histopathology and clinical parameters to enhance sperm retrieval (SR) prediction.MATERIALS AND METHODSWe reviewed 57 azoospermic men from Hanoi Medical University Hospital, recruited between January 2021 and September 2023. Inclusion criteria were confirmed azoospermia and exclusion of known NOA causes. All underwent mTESE with testicular biopsies classified into four histopathological patterns.RESULTSThe patients' mean age was 31.75 ± 5.19 years. SR was successful in 19.3% (11/57). Higher follicle-stimulating hormone (FSH) levels were noted in SR-positive men (p = 0.02). Sertoli cell-only syndrome (SCOS) was the most common pattern. While we found a significant difference in SR rate between testicular histopathology, multivariate analysis showed no strong association. However, FSH levels were predictive of histopathology patterns.CONCLUSIONSIdiopathic NOA (iNOA) represents over 60% of azoospermia cases. mTESE remains the gold standard, and FSH levels may help predict testicular histopathology patterns and improving patients prognosis of SR outcomes.

News (Medical) associated with Hanoi Medical University

12 May 2023

·www.healthcareitnews.com

Lululab launching AI beauty research centre with Yonsei Cancer Center

South Korean AI beauty service startup Lululab has tied up with Yonsei Cancer Center's Scar Laser and Plastic Surgery Center to take their research partnership on the use of AI to treat skin diseases to a new level. The organisations recently signed a memorandum of understanding to set up a Skin AI Beauty Research Center. According to a press statement, the research centre will serve as Lululab's bedrock of AI solutions for diagnosing skin diseases optimised for hospitals. It plans to market its technology to its overseas clients, which make up 90% of its client base. The facility will also be utilising Lululab's own AI-powered skin analysis tool for conducting research on various skin diseases, such as scar, atopy, and acne, and on the development of skin disease solutions. Lululab will also make use of its own AI-based customer relationship management system, which links skin analysis reports and treatment information to medical devices. WHY IT MATTERS Through the research centre, Lee Joo-hee, its upcoming head, said a predictive model to determine the potential effects of scarring and cosmetic treatments will be developed. He expects the technology to be applied to clinical practice soon. THE LARGER CONTEXT The latest MOU builds on Lululab's existing partnership with Yonsei University Severance Hospital where they jointly worked on a skin diseases database and AI-based tools for analysing skin diseases, including atopy, psoriasis, and vitiligo. Some of those AI tools are said to be ready for commercialisation. Outside South Korea, Lululab has another research partnership with Hanoi Medical University in Vietnam to co-develop similar AI-based skin disease analysis solutions, enabling the precise diagnosis of various skin diseases in the country.

100 Deals associated with Hanoi Medical University

100 Translational Medicine associated with Hanoi Medical University

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