Cancer-related pain is a common and challenging problem in patients with lung cancer, often requiring long-term pain management. Conventional pain treatments, including systemic medications, may not provide adequate relief or may cause significant side effects.
The erector spinae plane (ESP) block is a regional anesthesia technique that can help reduce pain by delivering local anesthetic near the nerves supplying the chest wall. This study aims to evaluate the effectiveness and safety of intermittent ESP block administered through a subcutaneous port for controlling cancer-related pain in patients with lung cancer.
Eligible patients with lung cancer and moderate to severe pain will receive intermittent ESP block injections via a subcutaneous port as part of their pain management plan. Pain intensity, analgesic requirements, and potential side effects will be assessed over time.
The results of this study may help determine whether intermittent ESP block via a subcutaneous port is a useful and feasible option for improving pain control and quality of life in patients with lung cancer.

Start Date01 Mar 2026

Sponsor / Collaborator

Hanoi Medical University

NCT07371481

/ Not yet recruitingNot ApplicableIIT

Results of Soft Tissue Grafting Around Implant in the Mandible Molar Area

This randomized controlled trial compares two techniques for peri-implant soft tissue augmentation in the mandibular molar region: an autogenous connective tissue graft (CTG) and a collagen matrix. Adult patients requiring implant treatment with insufficient peri-implant soft tissue thickness will be randomly assigned to receive either CTG or a collagen matrix at the time of implant surgery.
The study aims to evaluate and compare changes in peri-implant soft tissue thickness, width of keratinized tissue, and soft tissue contour over a 9-month follow-up period, as well as the occurrence of postoperative complications. The results of this study will help determine whether a collagen matrix can provide clinical outcomes comparable to those of connective tissue grafting for peri-implant soft tissue augmentation.

Start Date01 Feb 2026

Sponsor / Collaborator

Hanoi Medical University

NCT07369648

/ Not yet recruitingNot ApplicableIIT

Effects of Repetitive Transcranial Magnetic Stimulation Combined With Motor Rehabilitation on Motor and Functional Outcomes in Patients With Ischemic Stroke: A Randomized Sham-Controlled Trial

Ischemic stroke is a leading cause of long-term motor disability, frequently resulting in hemiplegia and limitations in daily activities and quality of life. Motor rehabilitation is a fundamental component of post-stroke care across all stages of recovery; however, functional outcomes may vary, particularly in patients with persistent motor impairment.
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation technique that has been used as an adjunct to rehabilitation to modulate cortical excitability and potentially support motor recovery.
The purpose of this study is to evaluate the effects of low-frequency rTMS combined with conventional motor rehabilitation compared with sham rTMS combined with conventional motor rehabilitation in patients with first-ever ischemic stroke during the acute, subacute, and chronic stages. Motor function, balance, functional mobility, activities of daily living, and stroke-specific quality of life will be assessed at baseline, after the intervention, and at 3-month and 6-month follow-up.

Start Date01 Feb 2026

Sponsor / Collaborator

Hanoi Medical University

100 Clinical Results associated with Hanoi Medical University

0 Patents (Medical) associated with Hanoi Medical University

2,070

Literatures (Medical) associated with Hanoi Medical University

01 Mar 2026·JPRAS open

Assessing donor site morbidity of the anterolateral thigh flap after extremity reconstruction

Article

Author: Ái, Vũ Hồng ; Nghĩa, Phan Tuấn ; Hưng, Ngô Thái ; Nam, Nguyễn Việt ; Sơn, Trần Thiết

The anterolateral thigh (ALT) flap has become a workhorse flap for plastic surgeons due to its versatility. These flaps comprise a significant amount of skin and soft tissue and feature a reliable vascular pedicle with a wide diameter, allowing for their use either freely or as a vascular pedicle. However, complications at the donor site can vary widely, affecting both the aesthetic appearance and functionality of the thigh, ranging from minor to more complex issues. This study evaluates the aesthetic and functional outcomes at donor sites for patients who underwent free ALT flap surgery to reconstruct limb soft tissue defects. A total of 97 ALT flaps were performed on 97 patients. The research examines various factors, including flap size, composition, and donor site closure techniques, to determine their impact on the aesthetics and functionality of the donor area. Early complications occurred in 11.3 % of the patients, including problems such as wound infections, wound margin necrosis, partial skin graft necrosis, and compartment syndrome. At a minimum 2-year follow-up, nearly all patients reported some degree of sensory reduction; however, none experienced local pain or significant sensory disturbances. Statistically significant differences were noted in thigh circumference and muscle strength between the donor and the contralateral thighs. Most patients reported satisfaction with their aesthetic results, though some, especially women, expressed dissatisfaction due to scarring. While early complications were generally mild and manageable, cosmetic outcomes could be negatively impacted by issues such as keloid scars and hypertrophy at the donor site, ultimately affecting patient satisfaction.

03 Feb 2026·CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Dietary Iron Intake and Risk of Gastric Cancer

Article

Author: Le, Ngoan Tran ; Nguyen, Thao Thanh ; Nguyen, Phuong Minh Thi ; Pham, Thanh Hoang ; Hoang, Anh Huy ; Nguyen, Bac Nhi ; Pham, Yen Thi-Hai ; Cullen, Jennifer ; Nguyen, Tin C. ; Nguyen, Ha ; Luu, Hung N. ; Nguyen, Tan Trong ; Nguyen, Thinh Gia

Abstract:

Background::

Iron is one of the essential elements for human life. Prior studies provided inconclusive results about the association between dietary iron intake and gastric cancer risk. We determined the association between dietary iron intake and the risk of gastric cancer in a case–control study of 1,182 incident gastric cancer cases and 2,965 controls in Vietnam.

Methods::

We used a validated, semiquantitative food frequency questionnaire to obtain dietary information, including dietary iron intake. An unconditional regression model was used to calculate OR and 95% confidence intervals (95% CI) of gastric cancer in relation to dietary iron intake, adjusted for potential confounders.

Results::

We observed a U-shaped association between dietary iron intake and gastric cancer risk. Compared with category 2 (reference group), the ORs and 95% CIs of category 1 (lowest intake) and categories 3, 4, 5, and 6 were 1.64 (1.27–2.12), 1.17 (0.90–1.53), 1.35 (1.01–1.82), 1.65 (1.18–2.31), and 2.00 (1.36–2.95; Ptrend < 0.001), respectively. This U-shaped association was also observed in both sexes, in all types of dietary iron intake (i.e., heme and nonheme), and among individuals with noncardia gastric cancer. This pattern was more apparent among individuals with a body mass index < 23 kg/m2 (Pheterogeneity = 0.02), never smokers (Pheterogeneity = 0.02), those without a family history of cancer (Pheterogeneity = 0.99), and individuals with blood group O (Pheterogeneity = 0.98) but showed up in both alcohol and coffee drinkers.

Conclusions::

We found a U-shaped association between dietary iron intake and gastric cancer risk.

Impact::

Results from our study also provide evidence for a tailored dietary intervention program that would benefit specific populations and those living in similar settings.

01 Feb 2026·JOURNAL OF ETHNOPHARMACOLOGY

Factors influencing severity and various clinical indexes in herb-induced liver injury: An updated bibliometric analysis and meta-analysis

Review

Author: Nguyen, Thu Nga ; Le, Nhat Thong ; Nguyen, Hoang An ; Duong, Doan Minh Trung ; Huynh, Thuc Quyen ; Le, Ngoc Vy ; Thao, Nguyen Phuong ; Do, Hien Thi Thu ; Tran, Doan Hong Ngoc ; Nguyen, Phuong-Hien ; Tran, Phillip ; Vu, Huyen Thanh ; Nguyen, Thi Thu Hoai ; Luong, Minh Hoang ; Huynh, Chan Khon ; Dao, Ngoc Bac ; Nguyen, Ha Linh ; Le, Minh Thong

ETHNOPHARMACOLOGICAL RELEVANCE:

The global rise in herbal medicine (HM) utilizes as an alternative treatment has corresponded with a rise in herb-induced liver injury (HILI). Although numerous systematic reviews existed, their generalizability is limited, and factors associated with HILI remain unclear.

AIM OF THE STUDY:

To comprehensively summarize HILI cases reported in English language literature and to investigate the association between potential factors related to HM use and the severity of liver injury.

MATERIALS AND METHODS:

A total of 643 patients from 382 studies were included. Global HILI cases rose markedly between 2002 and 2011. Weight management was the most common reason for HM use. Single-herb product users were more likely to develop mild injury compared with mixed-product users. Supplementary product use was associated with higher chances for having cholestasis. Females (64.9 %) were generally older at onset and had longer herb use durations, while males showed higher Gamma-Glutamyl Transferase (GGT) levels. Older patients tended to have less severe injury, though with elevated GGT and prolonged herb use. Race significantly influenced International Normalized Ratio, total bilirubin, and overall severity.

CONCLUSION:

This study highlights sex, age, race, usage patterns, liver function markers (GGT, INR, TBL), and HM type (herbal preparations and constituents) as key factors in HILI diagnosis and management. Further studies are warranted to confirm these associations.

News (Medical) associated with Hanoi Medical University

12 May 2023

·www.healthcareitnews.com

Lululab launching AI beauty research centre with Yonsei Cancer Center

South Korean AI beauty service startup Lululab has tied up with Yonsei Cancer Center's Scar Laser and Plastic Surgery Center to take their research partnership on the use of AI to treat skin diseases to a new level. The organisations recently signed a memorandum of understanding to set up a Skin AI Beauty Research Center. According to a press statement, the research centre will serve as Lululab's bedrock of AI solutions for diagnosing skin diseases optimised for hospitals. It plans to market its technology to its overseas clients, which make up 90% of its client base. The facility will also be utilising Lululab's own AI-powered skin analysis tool for conducting research on various skin diseases, such as scar, atopy, and acne, and on the development of skin disease solutions. Lululab will also make use of its own AI-based customer relationship management system, which links skin analysis reports and treatment information to medical devices. WHY IT MATTERS Through the research centre, Lee Joo-hee, its upcoming head, said a predictive model to determine the potential effects of scarring and cosmetic treatments will be developed. He expects the technology to be applied to clinical practice soon. THE LARGER CONTEXT The latest MOU builds on Lululab's existing partnership with Yonsei University Severance Hospital where they jointly worked on a skin diseases database and AI-based tools for analysing skin diseases, including atopy, psoriasis, and vitiligo. Some of those AI tools are said to be ready for commercialisation. Outside South Korea, Lululab has another research partnership with Hanoi Medical University in Vietnam to co-develop similar AI-based skin disease analysis solutions, enabling the precise diagnosis of various skin diseases in the country.

100 Deals associated with Hanoi Medical University

100 Translational Medicine associated with Hanoi Medical University

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