[Translation] A randomized, double-blind, placebo- and active-controlled Phase I/II clinical study to evaluate the safety, tolerability, immunogenicity and preliminary efficacy of JHM03 in subjects with moderate to severe glabellar lines
I期研究
主要研究目的:
评估JHM03在中、重度眉间纹受试者中的安全性和耐受性。
次要研究目的:
评估JHM03在中、重度眉间纹受试者中的免疫原性。
评估JHM03在中、重度眉间纹受试者中的初步有效性。
II期研究
主要研究目的:
评估JHM03在中、重度眉间纹受试者中的治疗后4周的有效性。
次要研究目的:
评估JHM03在中、重度眉间纹受试者中的其他方面的有效性。
评估JHM03在中、重度眉间纹受试者中的安全性。
评估JHM03在中、重度眉间纹受试者中的免疫原性。
[Translation] Phase I study
Main study objectives:
To evaluate the safety and tolerability of JHM03 in subjects with moderate and severe glabellar lines.
Secondary study objectives:
To evaluate the immunogenicity of JHM03 in subjects with moderate and severe glabellar lines.
To evaluate the preliminary efficacy of JHM03 in subjects with moderate and severe glabellar lines.
Phase II study
Main study objectives:
To evaluate the efficacy of JHM03 in subjects with moderate and severe glabellar lines 4 weeks after treatment.
Secondary study objectives:
To evaluate the efficacy of JHM03 in other aspects in subjects with moderate and severe glabellar lines.
To evaluate the safety of JHM03 in subjects with moderate and severe glabellar lines.
To evaluate the immunogenicity of JHM03 in subjects with moderate and severe glabellar lines.