[Translation] A randomized, single-blind, placebo-controlled exploratory clinical trial on the effects of piperphentonamine hydrochloride injection on hemodynamics in patients with heart failure after cardiac surgery
(1)以安慰剂为对照,探索注射用盐酸椒苯酮胺对心脏外科手术后心力衰竭患者血流动力学影响。 (2)了解注射用盐酸椒苯酮胺用于心脏外科手术后心力衰竭患者的药代动力学(PK)/药效动力学(PD)特点,进一步评价给药方案。
[Translation] (1) To explore the hemodynamic effects of piperphentonamine hydrochloride injection on patients with heart failure after cardiac surgery using placebo as control. (2) To understand the pharmacokinetic (PK)/pharmacodynamic (PD) characteristics of piperphentonamine hydrochloride injection in patients with heart failure after cardiac surgery and further evaluate the dosing regimen.