Delving into the Latest Updates on Suzhou Aosaikang Pharmaceutical Co. Ltd. with Synapse

Overview

Tags

Congenital Disorders

Endocrinology and Metabolic Disease

Eye Diseases

Bispecific antibody

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Endocrinology and Metabolic Disease	1

Top 5 Drug Type	Count

Bispecific antibody	1

Top 5 Target	Count

Ang2 x VEGF	1

主要目的：评价单次和多次玻璃体腔内注射（IVT）ASKG712在新生血管性年龄相关性黄斑变性（nAMD）患者中的安全性和耐受性。次要目的：评价单次和多次玻璃体腔内注射ASKG712在新生血管性年龄相关性黄斑变性患者中的药代动力学特征，为II期临床试验的给药方案提供依据。评价单次和多次玻璃体腔内注射ASKG712在新生血管性年龄相关性黄斑变性患者中免疫原性。评价单次和多次玻璃体腔内注射ASKG712在新生血管性年龄相关性黄斑变性患者中初步临床疗效。探索性目的：探索ASKG712治疗相关的生物标志物。

[Translation]

Primary objective: To evaluate the safety and tolerability of single and multiple intravitreal injections (IVT) of ASKG712 in patients with neovascular age-related macular degeneration (nAMD). Secondary objective: To evaluate the pharmacokinetic characteristics of single and multiple intravitreal injections of ASKG712 in patients with neovascular age-related macular degeneration, and provide a basis for the dosing regimen of the Phase II clinical trial. To evaluate the immunogenicity of single and multiple intravitreal injections of ASKG712 in patients with neovascular age-related macular degeneration. To evaluate the preliminary clinical efficacy of single and multiple intravitreal injections of ASKG712 in patients with neovascular age-related macular degeneration. Exploratory objective: To explore biomarkers related to ASKG712 treatment.

Start Date06 Feb 2023

Sponsor / Collaborator

Suzhou Aosaikang Pharmaceutical Co. Ltd.

100 Clinical Results associated with Suzhou Aosaikang Pharmaceutical Co. Ltd.

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0 Patents (Medical) associated with Suzhou Aosaikang Pharmaceutical Co. Ltd.

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100 Deals associated with Suzhou Aosaikang Pharmaceutical Co. Ltd.

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100 Translational Medicine associated with Suzhou Aosaikang Pharmaceutical Co. Ltd.

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Pipeline

Pipeline Snapshot as of 27 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Phase 1 Clinical

1

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