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MechanismOpioid receptors agonists |
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Inactive Indication- |
Drug Highest PhasePhase 2 |
First Approval Ctry. / Loc.- |
First Approval Date- |
/ Not yet recruitingPhase 2 盐酸噻吩诺啡片预防阿片类依赖者脱毒后复吸有效性与安全性的多中心、双盲、随机对照II期临床研究
[Translation] A multicenter, double-blind, randomized controlled phase II clinical study on the efficacy and safety of thiophene hydrochloride tablets in preventing relapse in opioid addicts after detoxification
通过评价盐酸噻吩诺啡片在阿片类依赖者脱毒后预防复吸的有效性与安全性,为后续试验给药方案确定提供科学依据.
[Translation] The effectiveness and safety of thiophene hydrochloride tablets in preventing relapse in opioid addicts after detoxification were evaluated to provide a scientific basis for determining the dosing regimen in subsequent trials.
/ Not yet recruitingPhase 2 应用盐酸丁丙诺啡片诱导引入盐酸噻吩诺啡片用于阿片类依赖防复吸探索性研究方案
[Translation] An exploratory study on the use of buprenorphine hydrochloride tablets to induce the introduction of thienorphine hydrochloride tablets for the prevention of relapse in opioid dependence
确定通过丁丙诺啡舌下片脱毒/诱导,再引入盐酸噻吩诺啡片的临床桥接方案,为噻吩诺啡控制阿片类依赖复吸的临床研究做准备。
[Translation] To determine a clinical bridging regimen of detoxification/induction with buprenorphine sublingual tablets followed by the introduction of thienorphine hydrochloride tablets, in preparation for clinical studies on thienorphine for controlling relapse of opioid dependence.
/ Unknown statusPhase 2IIT A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase Ⅱb Clinical Trial of Thienorphine Hydrochloride Tablets for the Efficacy, Safety, and Optimal Dosing of Relapse Prevention After Opioid Dependence Detoxification
Opioid addiction is common worldwide. Thienorphine hydrochloride is a newly partial opioid receptor agonist drugs. It's affinity with opioid receptors was much higher than opioids, which could effectively prevents opioid dependence by stop opioids competition for opioid receptors and causing opioid dependence. The aim of this research was to determine whether thienorphine hydrochloride would reduce opioid use and better preventing relapse among opioid addicts.
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