E-Scopics SAS

The objective of the study is to evaluate a new ultraportable ultrasound device, Hepatoscope, for the non-invasive assessment of hepatic steatosis in patients presenting with steatopathy from metabolic origin, by comparing its measurements with current diagnostic modalities, such as MRI PDFF.

Patients identified as being at risk of liver fibrosis because of a positive Fibrosis-4 (FIB-4) test in the primary care setting will be offered be enrolled in the trial and to undergo an Hepatoscope exam (external non-invasive ultrasound imaging exam) to screen for liver fibrosis (with stiffness measurements) and/or steatosis (with ultrasound parameters related to fatty liver). All patients presenting with a liver stiffness value of at least 6.5 kilopascal (kPa) will be referred to the tertiary hepatology consultations for further assessment. Hepatoscope measurements will be compared to the standard of care for these patients, as defined at the tertiary hepatology center.