Jiangsu Dongke Kangde Pharmaceutical Co., Ltd.

The main purpose of the study is to use the baricitinib tablets [trade name: Olumiant (艾乐明), 2 mg] licensed by Eli Lilly Nederland B.V. as the reference preparation and the baricitinib tablets held by Jiangsu Dongke Kangde Pharmaceutical Co., Ltd. as the test preparation to evaluate the human bioequivalence of the two preparations through a single-center, randomized, open, single-dose, two-preparation, two-sequence, two-cycle, double-crossover clinical study. Secondary purpose of the study: to observe the safety of the test preparation and the reference preparation in healthy Chinese subjects.

The main purpose of the study is to use the vonoprazan fumarate tablets produced by Jiangsu Dongke Kangde Pharmaceutical Co., Ltd. as the test preparation and the vonoprazan fumarate tablets (trade name: Walker, specification: 20 mg, calculated as C17H16FN3O2S) certified by Takeda Pharmaceutical Company Limited as the reference preparation. The bioequivalence of the two preparations under fasting and postprandial conditions is evaluated through a single-center, randomized, open, single-dose, two-preparation, two-sequence, two-period, double-crossover clinical study. Secondary purpose of the study: To observe the safety of the test preparation and the reference preparation in healthy Chinese subjects.

The main purpose of the study is to use Rosuvastatin Ezetimibe Tablets (I) (trade name: Zhilida, specifications: Rosuvastatin calcium 10 mg/Ezetimibe 10 mg) licensed by Sanofi-Aventis lreland Limited T/A SANOFI as the reference preparation and Rosuvastatin Ezetimibe Tablets (I) held by Jiangsu Dongke Kangde Pharmaceutical Co., Ltd. as the test preparation, and evaluate the bioequivalence of the two preparations under fasting and postprandial conditions through a single-center, randomized, open, single-dose, two-preparation, two-sequence, four-cycle, completely repeated crossover clinical study. Secondary purpose of the study: To observe the safety of the test preparation and the reference preparation in healthy Chinese subjects.