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/ Not yet recruitingPhase 2 SSGJ-707一线治疗PD-L1阳性的晚期非小细胞肺癌II期临床研究
[Translation] Phase II clinical study of SSGJ-707 as first-line treatment for advanced non-small cell lung cancer with PD-L1 positive
主要目的:
评估SSGJ-707不同给药方案在晚期非小细胞肺癌(NSCLC)受试者中的有效性
[Translation] Primary objective:
To evaluate the efficacy of different dosing regimens of SSGJ-707 in subjects with advanced non-small cell lung cancer (NSCLC)
评估SSGJ-707用于治疗晚期或转移性实体瘤患者的安全性、耐受性、药代动力学和抗肿瘤活性的开放、多中心、剂量递增和剂量扩展的Ⅰ期临床研究
[Translation] An open-label, multicenter, dose-escalation and dose-expansion Phase I clinical study to evaluate the safety, tolerability, pharmacokinetics and anti-tumor activity of SSGJ-707 in patients with advanced or metastatic solid tumors
Part 1:评估SSGJ-707在标准治疗无效/复发/无标准治疗/受试者拒绝标准治疗的晚期或转移性实体肿瘤受试者中的安全性和耐受性,并确定其RP2D;
Part 2:初步评估SSGJ-707在特定的晚期或转移性实体瘤受试者中的抗肿瘤疗效;
[Translation] Part 1: Evaluate the safety and tolerability of SSGJ-707 in subjects with advanced or metastatic solid tumors who have failed standard treatment/relapsed/have no standard treatment/refuse standard treatment, and determine its RP2D;
Part 2: Preliminary evaluation of the anti-tumor efficacy of SSGJ-707 in specific subjects with advanced or metastatic solid tumors;
100 Clinical Results associated with Dansheng Pharmaceutical Technology (Shanghai) Co., Ltd.
0 Patents (Medical) associated with Dansheng Pharmaceutical Technology (Shanghai) Co., Ltd.
The interior structure of the tablet is intricately designed to time the dosage release precisely. Credit: The University of Nottingham.
The University of Nottingham in the UK has announced the development of a new method enabling the creation of 3D-printed personalised pills.
The innovative technology has been developed by scientists from the university’s Centre for Additive Manufacturing and its Schools of Pharmacy and Life Sciences.
The technique utilises multi-material inkjet 3D printing to produce tablets with personalised drug release profiles, which can release drugs at a controlled rate.
It leverages a unique ink formulation based on molecules sensitive to ultraviolet light. Upon printing, these molecules form a water-soluble structure.
The interior structure of the tablet is intricately designed to time the dosage release precisely.
See Also:
SSGJ-707 by Dansheng Medical Technology (Shanghai) for Squamous Non-Small Cell Lung Cancer: Likelihood of Approval
SSGJ-707 by Dansheng Medical Technology (Shanghai) for Non-Small Cell Lung Cancer: Likelihood of Approval
Assistant Professor Dr Yinfeng He of the University of Nottingham’s Faculty of Engineering’s Centre for Additive Manufacturing stated: “This is an exciting step forward in the development of personalised medication.
“This breakthrough not only highlights the potential of 3D printing in revolutionising drug delivery but also opens up new avenues for the development of next-generation personalised medicines.”
The advancement is significant as it prints multiple drugs into a single tablet, streamlining complex medication regimens into one dose.
This approach could be advantageous for developing medications that require timed drug release – critical for treating certain diseases.
The potential for scalability of the approach was demonstrated by the ability to print 56 pills in a single batch.
Professor Felicity Rose of the University of Nottingham’s School of Pharmacy stated: “The future of prescribed medication lies in a personalised approach. We know that up to 50% of people in the UK alone don’t take their medicines correctly and this has an impact on poorer health outcomes with conditions not being controlled or properly treated.
“A single pill approach would simplify taking multiple medications at different times and this research is an exciting step towards that.”
100 Deals associated with Dansheng Pharmaceutical Technology (Shanghai) Co., Ltd.
100 Translational Medicine associated with Dansheng Pharmaceutical Technology (Shanghai) Co., Ltd.