Anhui Meilai Pharmaceutical Co., Ltd.

Healthy Chinese subjects were used as the test subjects. A self-crossover design was used to determine the time course of acipimox concentration in plasma after administration of acipimox capsules licensed by Anhui Meilai Pharmaceutical Co., Ltd. and produced by Bengbu Fengyuan Tushan Pharmaceutical Co., Ltd., and to estimate the corresponding pharmacokinetic parameters. Acipimox capsules (trade name: Olbetam®, specification: 0.25g) licensed by Pfizer Limited and produced by Pharmacia Italia SpA were used as reference to evaluate the bioequivalence between the preparations and to observe the safety of acipimox capsules in healthy Chinese subjects.