Impetis Biosciences Ltd. is an Indian company based in Mumbai that specializes in drug discovery and preclinical development services. Established in 2017, the company was formed through a spin-off from Advinus Therapeutics. Impetis Biosciences possesses valuable therapeutic candidates discovered by the skilled scientific team at Advinus. These potential treatments are aimed at addressing challenging therapeutic indications and are subject to various phases of trials and testing. The company's assets may have potential applications in auto-immune and inflammatory diseases, as well as oncology.

Disease Domain	Count

Immune System Diseases	7
Neoplasms	7
Endocrinology and Metabolic Disease	4
Nervous System Diseases	2
Hemic and Lymphatic Diseases	1

Top 5 Drug Type	Count

Small molecule drug	11
Unknown	2

Top 5 Target	Count

A2bR(Adenosine A2b receptor)	4
BTK(Tyrosine-protein kinase BTK)	2
A2aR(Adenosine A2a receptor)	1
RORγt(RAR-related orphan receptor gamma 2)	1
JAK1 x JAK3(Tyrosine-protein kinase JAK1 x Tyrosine-protein kinase JAK3)	1

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Pipeline

Pipeline Snapshot as of 04 Jul 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Preclinical

IND Application

Phase 1 Clinical

Current Projects

Drug(Targets)	Indications	Global Highest Phase

GKM-001 ( glucokinase )	Diabetes Mellitus, Type 2 More	Phase 1
PNQ-201 ( A2bR )	Colitis More	IND Application
PNQ-701 ( JAK1 )	Rheumatoid Arthritis More	IND Application
PNQ-370 ( A2aR )	Lung Cancer More	IND Application
PNQ-154 ( BTK C481S )	Neoplasms More	IND Application

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