Chengdu Nanshan Pharmaceutical Co., Ltd.

Three new acylphloroglucinol glycosides, hypericumols A - C, together with fifteen known phenolic derivatives, were isolated from the total phenolic extract of Hypericum japonicum. Hypericumols A, B, and C were characterized as 4,6-dimethyl-2-methylpropanoylphloroglucinol-1- O-β-D-glucopyranoside (1), 4-methyl-2-methylpropanoylphloroglucinol-1- O-β-D-glucopyranoside (2), and (2′ S)-4,6-dimethyl-2-methylbutyrylphloroglucinol-1- O-β-D-glucopyranoside (3), respectively, on the basis of spectroscopic data interpretation and chemical degradation reaction.