A review. The oral controlled absorption system (OCAS) is a new improved formulation/delivery system of tamsulosin, called Omnic OCAS. Omnic OCAS gels rapidly and hydrates completely in the upper gastro-intestinal tract which ensures continuous and consistent drug release throughput the entire length of the GI tract, also in the colon where water is poorly available. The outcomes of the two cardiovascular system challenge studies clearly show that Omnic OCAS 0.4 mg has improved pharmacokinetics which is accompanied by an improved cardiovascular safety (reduced risk of orthostatic hypotension) compared to conventional tamsulosin 0.4 mg.