Weifang Zhongshi Pharmaceutical Co. Ltd.

Primary objective: To evaluate the bioequivalence of oral flunarizine hydrochloride tablets in healthy Chinese adult male and female subjects after meals. Secondary objective: To evaluate the safety and tolerability of oral flunarizine hydrochloride tablets in the fed state.

Primary objective: To evaluate the bioequivalence of oral flunarizine hydrochloride tablets in healthy Chinese adult male and female subjects on an empty stomach. Secondary objective: To evaluate the safety and tolerability of oral flunarizine hydrochloride tablets on an empty stomach.

In this study, entecavir tablets (specification: 1 mg of entecavir) produced by Xiamen Deluqin Biotechnology Co., Ltd. were used as the test preparation, and entecavir tablets (specification: 1 mg of entecavir, trade name Boluding) produced by the original manufacturer Shanghai Bristol-Myers Squibb Pharmaceuticals Co., Ltd. were used as the reference preparation to evaluate the bioequivalence of the test preparation and the reference preparation under fasting conditions.