Delving into the Latest Updates on Nanometics LLC with Synapse

Overview

Tags

Respiratory Diseases

Neoplasms

Skin and Musculoskeletal Diseases

Small molecule drug

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Neoplasms	1

Top 5 Drug Type	Count

Small molecule drug	1

Top 5 Target	Count

BAX(Apoptosis regulator BAX)	1

This study is designed to determine the Sun Protection Factor (SPF) of a test product following 80 Minute Water Immersion methodology defined in Final Monograph - Code of Federal Regulations Title 21 - "Labeling and Effectiveness Testing; Sunscreen Drug Products; Required Labeling Based on Effectiveness Testing", Final Rule, 21 CFR 201.327.(j)

Start Date01 Sep 2021

Sponsor / Collaborator

Nanometics LLC

NCT01100463

/ CompletedPhase 1/2

A Phase 1-2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Pharmacokinetic Profile of 0.1% Uracil Topical Cream (UTC) in the Prevention of Hand-Foot Syndrome (HFS) in Patients With Metastatic Breast Cancer Treated With Capecitabine

The purpose of this research study is to see if combining uracil cream (UTC) with capecitabine (Xeloda) can prevent Hand-Foot Syndrome. The study will also see what effects UTC and capecitabine may have in patients with metastatic breast cancer.

Start Date01 Apr 2010

Sponsor / Collaborator

Nanometics LLC

100 Clinical Results associated with Nanometics LLC

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0 Patents (Medical) associated with Nanometics LLC

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5

Literatures (Medical) associated with Nanometics LLC

01 Apr 2022·Journal of the American Academy of DermatologyQ1 · MEDICINE

Frequency of procedural and medical treatments of actinic keratosis

Q1 · MEDICINE

Letter

Author: Ranpariya, Varun K ; Feldman, Steven R ; Muddasani, Suraj ; Mahon, Andrew B

Cosmetics & Toiletries

Peptidomimetics for cosmetic applications

Author: Shin, Sung Bin Y. ; Isaacman, Steven ; Isaacman, Michael

A review.This article discusses the potential application of these short chain oligomers in cosmetics and personal care.Peptidomimetics utilize non-natural oligomer backbones, making them resistant to both exo- and endopeptidases.Bioactive peptides are capable of inducing biol. responses by stimulating cell surface receptors, inhibiting protein-protein interactions, inducing protein conformational rearrangements, inactivating enzymes, regulating gene expression levels, etc.

Cosmetics & Toiletries

Smart materials for triggered release of cosmetics

Author: Isaacman, Steven ; Isaacman, Michael

A review.This article discusses the smart materials for triggered release of cosmetics.Though these synthetic systems are rudimentary compared with the responsive mechanisms found in nature, their complexities are rapidly increasing and furthering the development of highly selective and sensitive materials.Multitriggered systems capable of responding to systematic stimuli for the release of therapeutic agents in vivo are exciting frontiers in bioengineering, materials science and personal care; although caveats exist such as the need for stringent preparation methods, including controlled lighting, pH or temperature, depending on the stimuli-responsive polymer used.

100 Deals associated with Nanometics LLC

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100 Translational Medicine associated with Nanometics LLC

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Pipeline

Pipeline Snapshot as of 26 Jan 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Preclinical

1

3

Other

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

GL-0385 ( BAX )	Lung Cancer More	Preclinical
NM-96	Anemia, Sickle Cell More	Pending
AIC-6020 ( Hemoglobins )	Vaso-occlusive crisis More	Pending
Uracil	Hand-Foot Syndrome More	Pending