Delving into the Latest Updates on Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd. with Synapse

Overview

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Neoplasms

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Small molecule drug

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Disease Domain	Count

Neoplasms	2

Top 5 Drug Type	Count

Small molecule drug	3

主要目的：评价注射用 GMDTC 给药后在镉超标人群中的药效动力学特征；次要目的：评价注射用 GMDTC 在镉超标人群中多次给药的安全性、耐受性及药代动力学特征；探索性目的：评价与安慰剂相比，注射用 GMDTC 在镉超标人群中肾脏功能早期损伤的改善。

[Translation]

Primary objective: To evaluate the pharmacodynamic characteristics of GMDTC for injection in people with excessive cadmium levels after administration; Secondary objective: To evaluate the safety, tolerability and pharmacokinetic characteristics of GMDTC for injection after multiple administration in people with excessive cadmium levels; Exploratory objective: To evaluate the improvement of early renal function damage in people with excessive cadmium levels by GMDTC for injection compared with placebo.

Start Date07 Jul 2025

Sponsor / Collaborator

Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.

NCT06572566

/ RecruitingNot Applicable

Study on the Mechanism of Action of Chemical Category 1 Innovative Drug GMDTC on Neuropsychiatric Behavior in Cadmium-exposed People

This study hypothesized that excessive cadmium is related to clinical pain, depression, and cognitive impairment, and that related indicators will improve after cadmium is eliminated.

Start Date08 Jan 2024

Sponsor / Collaborator

Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.

CTR20234320

/ CompletedPhase 1

注射用GMDTC在镉超标人群中多次给药的安全性、耐受性和药代动力学特征Ⅰb期临床研究

[Translation] Phase Ib clinical study on the safety, tolerability and pharmacokinetic characteristics of multiple administrations of GMDTC for injection in people with excessive cadmium levels

主要目的：评价注射用GMDTC在镉超标人群中多次给药的安全性和耐受性；次要目的：评价注射用GMDTC在镉超标人群中多次给药的药代动力学特征和药效动力学特征。

[Translation]

Primary purpose: To evaluate the safety and tolerability of multiple administrations of GMDTC for injection in people with excessive cadmium levels; Secondary purpose: To evaluate the pharmacokinetic and pharmacodynamic characteristics of multiple administrations of GMDTC for injection in people with excessive cadmium levels.

Start Date08 Jan 2024

Sponsor / Collaborator

Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.

100 Clinical Results associated with Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.

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0 Patents (Medical) associated with Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.

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100 Deals associated with Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.

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100 Translational Medicine associated with Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.

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Pipeline

Pipeline Snapshot as of 04 Apr 2026

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Discovery

2

1

Phase 2

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