Shijiazhuang Exploration Pharmaceutical Technology Co., Ltd

Primary objective: To compare the differences in absorption extent and rate of loxoprofen sodium patch (test preparation T, specification: 100 mg/patch (10 cm×14 cm)) provided by Shijiazhuang Exploration Pharmaceutical Technology Co., Ltd. and loxoprofen sodium patch (reference preparation R, trade name: Lesong®, specification: 100 mg/patch (10 cm×14 cm)) produced by LEAD CHEMICAL CO., LTD. HISAGANE PLANT in healthy subjects under single application conditions. Statistical analysis of the main pharmacokinetic parameters was used to evaluate whether the two were bioequivalent. Secondary objective: To evaluate the safety, adhesion firmness and skin reactivity of loxoprofen sodium patch by observing the safety indicators and adhesion firmness and skin reactivity scores at different time points after single application of the test preparation and reference preparation in healthy subjects.