[Translation] A randomized, double-blind, placebo-controlled, single-dose escalation Phase I clinical study to evaluate the safety, tolerability and efficacy of ZGHUMSC001 in patients with knee osteoarthritis
主要目的:评估膝骨关节炎患者单次关节腔注射不同剂量ZGHUMSC001后的安全性、耐受性,并确定后期试验推荐剂量。
次要目的:初步评估膝骨关节炎患者单次关节腔注射不同剂量ZGHUMSC001后的有效性。
[Translation] Primary objective: To evaluate the safety and tolerability of different doses of ZGHUMSC001 after a single intra-articular injection in patients with knee osteoarthritis, and to determine the recommended dose for later trials.
Secondary objective: To preliminarily evaluate the effectiveness of different doses of ZGHUMSC001 after a single intra-articular injection in patients with knee osteoarthritis.