Abstract : This study is designed to explore the association between age, gender, smoking, diabetes, hypertension, cholesterol, and HDL levels with the number of obstructed coronaries and obstruction severity in patients presenting with CAD. A cross-sectional study included 100 patients collected by convenient sampling from Ghazi Al-Hariri and Ibn-Albitar hospitals in Baghdad from July 1 to August 30, 2021. Data were collected via a questionnaire and analyzed using SPSS v2 with a p-value of < 0.05 considered significant. Of the 100 patients, 61 were men and 39 were women; gender had no statistically significant association with either the increased number of obstructed arteries or obstruction severity. Forty-one of the patients were smokers, 62 were diabetics, and 63 were hypertensive; each of these categories was found to be significantly associated with the mentioned study variables with a p-value of < 0.05. Age and duration of both smoking and diabetes were also found to have a significant association With a p-value of 0.05, 39% of the patients had elevated cholesterol and 99% had low HDL levels; their relationship with both study variables was significant. The relationship of obstruction severity to these factors was also tested for each coronary artery individually; the results for each artery had variable significance, except for LCX, which was significant in all risks. All of the assessed risk factors were found to be significantly associated with an increasing number of obstructed coronaries together with obstruction severity, namely age, smoking, diabetes, hypertension, cholesterol, and HDL, except for gender, which did not show any significance in our study.