Last update 01 Nov 2024

HASPIN

Basic Info

Synonyms
germ cell associated 2 (haspin), Germ cell-specific gene 2 protein, GSG2
+ [5]
Introduction
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.

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