Synonyms Brachyury protein, Protein T, T + [2] |
Introduction Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site. |
Target |
Mechanism CEA inhibitors [+3] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhasePhase 2 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Target |
Mechanism TBXT modulators |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhasePhase 2 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Target |
Mechanism TBXT modulators |
Active Org. |
Originator Org. |
Active Indication |
Drug Highest PhasePhase 1 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Start Date01 Apr 2024 |
Sponsor / Collaborator |
Start Date08 May 2023 |
Sponsor / Collaborator |
Start Date04 May 2021 |
Sponsor / Collaborator |