Last update 01 Nov 2024

CLEC9A

Basic Info

Synonyms
C-type lectin domain containing 9A, C-type lectin domain family 9 member A, CD370
+ [4]
Introduction
Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.

Analysis

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