Clinical Trials associated with KCNQ (Kv7) x GABAA receptor
NCT04912856
/ TerminatedPhase 3
An Open-Label Extension of the Study XEN496 in Children With KCNQ2 Developmental and Epileptic Encephalopathy
To assess the long-term safety and tolerability of XEN496 in pediatric subjects with KCNQ2 developmental and epileptic encephalopathy (KCNQ2-DEE) who had participated in the primary study (XPF-009-301).
A Phase 3 Study of Adjunctive XEN496 in Pediatric Subjects With KCNQ2 Developmental and Epileptic Encephalopathy
To investigate the potential antiseizure effects of adjunctive XEN496 (ezogabine) compared with placebo in children with KCNQ2 Developmental and Epileptic Encephalopathy (KCNQ2-DEE).
Main research purpose: This study used retigabine tablets (50 mg) produced by Tianjin Hongri Pharmaceutical Co., Ltd. as the test preparation to evaluate its preliminary pharmacokinetic characteristics after administration under fasting conditions.
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