|
|
|
|
|
Inactive Indication- |
Drug Highest PhasePhase 1 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
/ RecruitingNot ApplicableIIT A first-in-human dose-escalation and expansion study with the antibody-drug conjugate BYON3521 to evaluate the safety, pharmacokinetics and efficacy in patients with c-MET expressing locally advanced or metastatic solid tumours. - Phase1 study in patients with advanced or metastatic solid tumours
Start Date11 Jul 2022 |
Sponsor / Collaborator- |
/ Active, not recruitingPhase 1 A First-in-human Dose-escalation and Expansion Trial With the Antibody-drug Conjugate BYON3521 to Evaluate the Safety, Pharmacokinetics and Efficacy in Patients With c-MET Expressing Locally Advanced or Metastatic Solid Tumours
This is the first-in-human trial with BYON3521, an antibody-drug conjugate (ADC) comprising a humanized IgG1 monoclonal antibody directed against the c-MET receptor covalently conjugated to a duocarmycin-containing linker-drug.
100 Clinical Results associated with c-Met x DNA
100 Translational Medicine associated with c-Met x DNA
0 Patents (Medical) associated with c-Met x DNA