Last update 01 Nov 2024

THBD

Basic Info

Synonyms
BDCA-3, CD141, Fetomodulin
+ [5]
Introduction
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Analysis

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