Synonyms Mel-1A-R, Mel1a receptor, melatonin receptor 1A + [3] |
Introduction High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
Target |
Mechanism MTNR1A agonists [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date22 Jul 2005 |
Mechanism MAO-A inhibitors [+2] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Start Date19 Sep 2024 |
Sponsor / Collaborator |
Start Date05 Sep 2024 |
Sponsor / Collaborator- |
Start Date01 Aug 2024 |
Sponsor / Collaborator |