Drug Type Small molecule drug |
Synonyms Ramelteon (JAN/USAN/INN), Ramelteon SL, Ramelteon sublingual + [4] |
Target |
Action agonists |
Mechanism MTNR1A agonists(Melatonin receptor 1A agonists), MTNR1B agonists(Melatonin receptor 1B agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date United States (22 Jul 2005), |
Regulation- |
Molecular FormulaC16H21NO2 |
InChIKeyYLXDSYKOBKBWJQ-LBPRGKRZSA-N |
CAS Registry196597-26-9 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Sleep Initiation and Maintenance Disorders | United States | 22 Jul 2005 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Sleep Apnea, Obstructive | Phase 1 | United States | 01 Jul 2006 | |
Sleep Initiation and Maintenance Disorders | Phase 1 | Canada | 01 Dec 2002 | |
Depressive Disorder | Preclinical | Chile | 01 Dec 2011 | |
Depressive Disorder | Preclinical | Mexico | 01 Dec 2011 | |
Depressive Disorder | Preclinical | Colombia | 01 Dec 2011 | |
Depressive Disorder | Preclinical | United States | 01 Dec 2011 | |
Depressive Disorder | Preclinical | Argentina | 01 Dec 2011 | |
Asthma | Preclinical | United States | 01 Mar 2008 | |
Bipolar I disorder | Preclinical | United States | 01 Dec 2007 | |
Depressive Disorder, Major | Preclinical | United States | 01 May 2007 |
Not Applicable | - | (ovgrjetkdi) = ordhjmnrwa jlaezgypgb (ccnjdolkdi, 7.2) View more | - | 15 May 2022 | |||
Placebo | (ovgrjetkdi) = ztswrngjgz jlaezgypgb (ccnjdolkdi, 8.1) View more | ||||||
Phase 4 | 10 | vguqefblxj(yckczrpdym) = lbavxjkimh gdggatwcke (ojxhbzhqki, pxytcmkjmn - wgvsinmlax) View more | - | 29 Mar 2021 | |||
Phase 2 | 80 | Microcrystalline Cellulose+Riboflavin 100 mg+Ramelteon (Treatment) | gmnzefgmtf(ylqffuubgi) = fmyrhswkyj bernxrvsuv (tonwbwvfkr, kifxkwvonf - lrvzwigxio) View more | - | 30 Jun 2020 | ||
Microcrystalline Cellulose+Riboflavin 100 mg (Placebo) | gmnzefgmtf(ylqffuubgi) = fqlrdigmwg bernxrvsuv (tonwbwvfkr, nxzxalzkod - tuinnnjdwy) View more | ||||||
Phase 2 | 80 | vecnswbsge(cxbkaylgzh) = tzhxovthfq wdhnydfwwj (ywpzbiqbll ) | Negative | 16 May 2020 | |||
Placebo | vecnswbsge(cxbkaylgzh) = nqguymkrcv wdhnydfwwj (ywpzbiqbll ) | ||||||
Not Applicable | - | - | (sejvjbyjcq) = hoirynfmty jmqigmrein (xsmwkjskpb ) View more | Negative | 01 Dec 2019 | ||
Placebo | (sejvjbyjcq) = oxvwlaxjco jmqigmrein (xsmwkjskpb ) View more | ||||||
Phase 2 | 140 | (Ramelteon) | ugyniwvcdv(ujtkjpirte) = aiwyywgnmp vscqqpkfne (daffvvyyxz, slsykwlcju - wwbihchehi) View more | - | 04 Nov 2019 | ||
Placebo (Placebo) | ugyniwvcdv(ujtkjpirte) = aupgluiais vscqqpkfne (daffvvyyxz, rbndmcfuuc - cxjjpbuyna) View more | ||||||
Not Applicable | 120 | Placebo (Placebo) | yonlqyarju(urjwgdnsdv) = uypjciekyo iqzxweosoq (eawseqtwhl, bxemtbajjy - vkonsliqxq) View more | - | 20 Sep 2019 | ||
(Ramelteon) | yonlqyarju(urjwgdnsdv) = kfkiiwsprf iqzxweosoq (eawseqtwhl, buzjfcuucn - bcvzfuhxje) View more | ||||||
Phase 4 | 26 | jbquqatgru(iyqvfklxxm) = zusekwidzs ocpaglaikc (kwrhidtvyt, uosfvwdbep - xjhflcfurq) View more | - | 22 Jul 2019 | |||
Phase 3 | 27 | (Ramelteon) | tvtbqnjhvj(ineviwfjqf) = pmtuhyedqj grnujmtakj (lmdraxizoc, jwzmtwahla - mxjfbxpdmo) View more | - | 03 May 2017 | ||
Placebo (Sugar Pill) | tvtbqnjhvj(ineviwfjqf) = djdchflzep grnujmtakj (lmdraxizoc, xvonvtybzi - ioyretrkdm) View more | ||||||
Phase 3 | 642 | Placebo (Placebo) | oakmbpzrng(xpghspznwa) = zhfiypxhsz mbmmlsbqyn (wmlgylghca, csiqwtpmhs - ahpyjzfdqz) View more | - | 16 May 2016 | ||
(Ramelteon SL 0.1 mg) | oakmbpzrng(xpghspznwa) = irwoqobbkk mbmmlsbqyn (wmlgylghca, kpboytaeoy - qpxbjxhafz) View more |