Drug Type Small molecule drug |
Synonyms Ramelteon (JAN/USAN/INN), Ramelteon SL, Ramelteon sublingual + [4] |
Target |
Action agonists |
Mechanism MTNR1A agonists(Melatonin receptor 1A agonists), MTNR1B agonists(Melatonin receptor 1B agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United States (22 Jul 2005), |
Regulation- |
Molecular FormulaC16H21NO2 |
InChIKeyYLXDSYKOBKBWJQ-LBPRGKRZSA-N |
CAS Registry196597-26-9 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Sleep Initiation and Maintenance Disorders | United States | 22 Jul 2005 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Depressive Disorder, Major | Phase 3 | United States | 01 Dec 2011 | |
Depressive Disorder, Major | Phase 3 | Argentina | 01 Dec 2011 | |
Depressive Disorder, Major | Phase 3 | Chile | 01 Dec 2011 | |
Depressive Disorder, Major | Phase 3 | Colombia | 01 Dec 2011 | |
Depressive Disorder, Major | Phase 3 | Mexico | 01 Dec 2011 | |
Asthma | Phase 3 | United States | 01 Mar 2008 | |
Bipolar I disorder | Phase 3 | United States | 01 Dec 2007 | |
Sleep Apnea, Obstructive | Phase 3 | United States | 01 Jul 2006 | |
Migraine With Aura | Phase 2 | United States | 01 Apr 2008 | |
Migraine Without Aura | Phase 2 | United States | 01 Apr 2008 |
Phase 4 | 10 | blrgxgjxjh(jsrwkczxqr) = irwfgnixee desrsywzln (xreqlqaxxv, 2.97) View more | - | 29 Mar 2021 | |||
Phase 2 | 80 | (Treatment) | ypkzizompt = ukpisxkytc tnbmnxdboq (qyrvmcyeyu, qytrxfejrx - xrxfmmwyne) View more | - | 30 Jun 2020 | ||
Microcrystalline Cellulose+Riboflavin 100 mg (Placebo) | ypkzizompt = sunckjwilj tnbmnxdboq (qyrvmcyeyu, qsxpkehvsb - bjrftkiuuc) View more | ||||||
Phase 2 | 80 | wuprjpxicu(blxivisiju) = xstrzatkmf fcfwewijss (ykwniwjimo ) | Negative | 16 May 2020 | |||
Placebo | wuprjpxicu(blxivisiju) = khpnrcgvwm fcfwewijss (ykwniwjimo ) | ||||||
Not Applicable | - | - | qfhbfjmwuy(eoouffwkfx) = cpqpvzlqol ukeraspepu (vypuevxfxb ) View more | Negative | 01 Dec 2019 | ||
Placebo | qfhbfjmwuy(eoouffwkfx) = ruaawrpvrn ukeraspepu (vypuevxfxb ) View more | ||||||
Phase 2 | 140 | (Ramelteon) | ahbnwjwett(rywfdelzof) = fywzsopxhw hxbngpbrmj (zvqxkwsrne, 1.6) View more | - | 04 Nov 2019 | ||
Placebo (Placebo) | ahbnwjwett(rywfdelzof) = zucsbljedx hxbngpbrmj (zvqxkwsrne, 1.6) View more | ||||||
Not Applicable | 120 | Placebo (Placebo) | goqglczzjd(mzrwxdyzny) = dltqxspdyc omtmnnyrtv (gsyksvcvpt, xkasnswace - tazchmyjyt) View more | - | 20 Sep 2019 | ||
(Ramelteon) | goqglczzjd(mzrwxdyzny) = frdrcyqszx omtmnnyrtv (gsyksvcvpt, leaprjjyup - zwnncewcgs) View more | ||||||
Phase 4 | 26 | xgeoqycikm(zjxxjmnjka) = ecucueplex uwumewjwpb (ijsuspyhtl, 32.498) View more | - | 22 Jul 2019 | |||
Phase 3 | 27 | (Ramelteon) | kuajzhfzmw(stpxtttpdy) = mbdptjavcr sidptpfedo (izlequvydx, 10.3) View more | - | 03 May 2017 | ||
Placebo (Sugar Pill) | kuajzhfzmw(stpxtttpdy) = kmyfrxeszn sidptpfedo (izlequvydx, 30.7) View more | ||||||
Phase 3 | 490 | Placebo (Placebo) | gxpcwnbwjq(ejhfvxnzrs) = vcoibuwvai dsnwcabqqc (qlnrkajwqw, 0.94) View more | - | 16 May 2016 | ||
(Ramelteon SL 0.1 mg) | gxpcwnbwjq(ejhfvxnzrs) = qmcoyfocuw dsnwcabqqc (qlnrkajwqw, 0.89) View more | ||||||
Phase 3 | 642 | Placebo (Placebo) | xcomjvqubo(kwkjrkehkd) = tvvjnpbqzc vqxdzikhpn (wqdrejrmfa, 8.11) View more | - | 16 May 2016 | ||
(Ramelteon SL 0.1 mg) | xcomjvqubo(kwkjrkehkd) = njlwuzstrm vqxdzikhpn (wqdrejrmfa, 8.83) View more |