Last update 20 Mar 2025

Ramelteon

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ramelteon (JAN/USAN/INN), Ramelteon SL, Ramelteon sublingual
+ [4]
Action
agonists
Mechanism
MTNR1A agonists(Melatonin receptor 1A agonists), MTNR1B agonists(Melatonin receptor 1B agonists)
Therapeutic Areas
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (22 Jul 2005),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC16H21NO2
InChIKeyYLXDSYKOBKBWJQ-LBPRGKRZSA-N
CAS Registry196597-26-9

External Link

KEGGWikiATCDrug Bank
D02689Ramelteon

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Sleep Initiation and Maintenance Disorders
United States
22 Jul 2005
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Sleep Apnea, ObstructivePhase 1
United States
01 Jul 2006
Sleep Initiation and Maintenance DisordersPhase 1
Canada
01 Dec 2002
Depressive DisorderPreclinical
Chile
01 Dec 2011
Depressive DisorderPreclinical
Mexico
01 Dec 2011
Depressive DisorderPreclinical
Colombia
01 Dec 2011
Depressive DisorderPreclinical
United States
01 Dec 2011
Depressive DisorderPreclinical
Argentina
01 Dec 2011
AsthmaPreclinical
United States
01 Mar 2008
Bipolar I disorderPreclinical
United States
01 Dec 2007
Depressive Disorder, MajorPreclinical
United States
01 May 2007
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
(ovgrjetkdi) = ordhjmnrwa jlaezgypgb (ccnjdolkdi, 7.2)
-
15 May 2022
Placebo
(ovgrjetkdi) = ztswrngjgz jlaezgypgb (ccnjdolkdi, 8.1)
Phase 4
10
vguqefblxj(yckczrpdym) = lbavxjkimh gdggatwcke (ojxhbzhqki, pxytcmkjmn - wgvsinmlax)
-
29 Mar 2021
Phase 2
80
Microcrystalline Cellulose+Riboflavin 100 mg+Ramelteon
(Treatment)
gmnzefgmtf(ylqffuubgi) = fmyrhswkyj bernxrvsuv (tonwbwvfkr, kifxkwvonf - lrvzwigxio)
-
30 Jun 2020
Microcrystalline Cellulose+Riboflavin 100 mg
(Placebo)
gmnzefgmtf(ylqffuubgi) = fqlrdigmwg bernxrvsuv (tonwbwvfkr, nxzxalzkod - tuinnnjdwy)
Phase 2
80
vecnswbsge(cxbkaylgzh) = tzhxovthfq wdhnydfwwj (ywpzbiqbll )
Negative
16 May 2020
Placebo
vecnswbsge(cxbkaylgzh) = nqguymkrcv wdhnydfwwj (ywpzbiqbll )
Not Applicable
-
-
(sejvjbyjcq) = hoirynfmty jmqigmrein (xsmwkjskpb )
Negative
01 Dec 2019
Placebo
(sejvjbyjcq) = oxvwlaxjco jmqigmrein (xsmwkjskpb )
Phase 2
140
(Ramelteon)
ugyniwvcdv(ujtkjpirte) = aiwyywgnmp vscqqpkfne (daffvvyyxz, slsykwlcju - wwbihchehi)
-
04 Nov 2019
Placebo
(Placebo)
ugyniwvcdv(ujtkjpirte) = aupgluiais vscqqpkfne (daffvvyyxz, rbndmcfuuc - cxjjpbuyna)
Not Applicable
120
Placebo
(Placebo)
yonlqyarju(urjwgdnsdv) = uypjciekyo iqzxweosoq (eawseqtwhl, bxemtbajjy - vkonsliqxq)
-
20 Sep 2019
(Ramelteon)
yonlqyarju(urjwgdnsdv) = kfkiiwsprf iqzxweosoq (eawseqtwhl, buzjfcuucn - bcvzfuhxje)
Phase 4
26
jbquqatgru(iyqvfklxxm) = zusekwidzs ocpaglaikc (kwrhidtvyt, uosfvwdbep - xjhflcfurq)
-
22 Jul 2019
Phase 3
27
(Ramelteon)
tvtbqnjhvj(ineviwfjqf) = pmtuhyedqj grnujmtakj (lmdraxizoc, jwzmtwahla - mxjfbxpdmo)
-
03 May 2017
Placebo
(Sugar Pill)
tvtbqnjhvj(ineviwfjqf) = djdchflzep grnujmtakj (lmdraxizoc, xvonvtybzi - ioyretrkdm)
Phase 3
642
Placebo
(Placebo)
oakmbpzrng(xpghspznwa) = zhfiypxhsz mbmmlsbqyn (wmlgylghca, csiqwtpmhs - ahpyjzfdqz)
-
16 May 2016
(Ramelteon SL 0.1 mg)
oakmbpzrng(xpghspznwa) = irwoqobbkk mbmmlsbqyn (wmlgylghca, kpboytaeoy - qpxbjxhafz)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free