Last update 01 Nov 2024
GAK x EphA2
Last update 01 Nov 2024
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Target |
Mechanism |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest Phase |
First Approval Ctry. / Loc. |
First Approval Date |
100 Clinical Results associated with GAK x EphA2
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100 Translational Medicine associated with GAK x EphA2
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08 Aug 2024Journal of Medicinal Chemistry
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors
Article
Author: Zhubi, Rezart ; Karim, Marwah ; Tran, Do Hoang Nhu ; Saxena, Krishna ; Berger, Benedict-Tilman ; Joerger, Andreas C ; Einav, Shirit ; Krämer, Andreas ; Ehret, Theresa A L ; Lenz, Christopher ; Elson, Lewis ; Berger, Lena M ; Knapp, Stefan ; Gerninghaus, Joshua ; Hanke, Thomas ; Müller, Susanne ; Schreiber, Christian
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