Last update 01 Nov 2024

YAP1 x p53 x NF-κB x FACT

Basic Info

Related Targets
YAP1p53NF-κB[+1]

Related

1
Drugs associated with YAP1 x p53 x NF-κB x FACT
CBL-0137
Target
FACT x NF-κB x YAP1 x p53
Mechanism
FACT antagonists [+3]
Active Org.
Incuron LLCIncuron LLC [+1]
Originator Org.
Cleveland BioLabs, Inc.Cleveland BioLabs, Inc.
Active Indication
Diffuse Intrinsic Pontine Glioma [+8]
Inactive Indication
Advanced Malignant Solid Neoplasm [+4]
Drug Highest PhasePhase 1/2
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
5
Clinical Trials associated with YAP1 x p53 x NF-κB x FACT
NCT05498792 / SuspendedEarly Phase 1IIT
MEL-212: A Phase I Proof-of-Concept Study of CBL0137 (Curaxin) Combined With Ipilimumab and Nivolumab Therapy in Locally Advanced or Metastatic Melanoma
100 Clinical Results associated with YAP1 x p53 x NF-κB x FACT
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100 Translational Medicine associated with YAP1 x p53 x NF-κB x FACT
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0 Patents (Medical) associated with YAP1 x p53 x NF-κB x FACT
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