Last update 01 Nov 2024

NAMPT x CLDN18.2 x NKG2D x NMDA receptor x GluN2B

Basic Info

Related Targets
NAMPTCLDN18.2NKG2D[+2]

Related

1
Drugs associated with NAMPT x CLDN18.2 x NKG2D x NMDA receptor x GluN2B
KD-496
Target
CLDN18.2 x GluN2B x NAMPT x NKG2D x NMDA receptor
Mechanism
CLDN18.2 inhibitors [+6]
Active Org.
Nanjing KAEDI Biotech, Inc. [+2]
Originator Org.
Nanjing KAEDI Biotech, Inc.Nanjing KAEDI Biotech, Inc.
Active Indication
CLDN18.2 positive Solid Tumors [+3]
Inactive Indication-
Drug Highest PhasePhase 1
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
2
Clinical Trials associated with NAMPT x CLDN18.2 x NKG2D x NMDA receptor x GluN2B
NCT06134960 / Not yet recruitingPhase 1IIT
A Single-center, Open-label, Single-arm Clinical Study of the Safety and Efficacy of KD-496 CAR-T Therapy in Advanced NKG2DL+/CLDN18.2+ Solid Tumors
NCT05583201 / RecruitingEarly Phase 1IIT
A Single-center, Open-label, Single-arm Clinical Study of the Safety and Efficacy of KD-496 CAR-T Therapy in Advanced NKG2DL+/CLDN18.2+ Solid Tumors
100 Clinical Results associated with NAMPT x CLDN18.2 x NKG2D x NMDA receptor x GluN2B
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100 Translational Medicine associated with NAMPT x CLDN18.2 x NKG2D x NMDA receptor x GluN2B
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0 Patents (Medical) associated with NAMPT x CLDN18.2 x NKG2D x NMDA receptor x GluN2B
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