Last update 01 Nov 2024

CDK13 x CDK12 x CDK9 x HDAC3 x HDAC2 x HDAC1

Basic Info

Related Targets
CDK13CDK12CDK9[+3]

Related

1
Drugs associated with CDK13 x CDK12 x CDK9 x HDAC3 x HDAC2 x HDAC1
Compound 33a (Nankai University)
Target
CDK12 x CDK13 x CDK9 x HDAC1 x HDAC2 x HDAC3
Mechanism
CDK12 inhibitors [+5]
Active Org.
Nankai UniversityNankai University
Originator Org.
Nankai UniversityNankai University
Active Indication
Acute Myeloid Leukemia
Inactive Indication-
Drug Highest PhasePreclinical
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
100 Clinical Results associated with CDK13 x CDK12 x CDK9 x HDAC3 x HDAC2 x HDAC1
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100 Translational Medicine associated with CDK13 x CDK12 x CDK9 x HDAC3 x HDAC2 x HDAC1
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0 Patents (Medical) associated with CDK13 x CDK12 x CDK9 x HDAC3 x HDAC2 x HDAC1
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1
Literatures (Medical) associated with CDK13 x CDK12 x CDK9 x HDAC3 x HDAC2 x HDAC1
01 Mar 2023European Journal of Medicinal Chemistry
Discovery of novel and bioavailable histone deacetylases and cyclin-dependent kinases dual inhibitor to impair the stemness of leukemia cells

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