Last update 08 May 2025

CPA1

Basic Info

Synonyms
Carboxypeptidase A1, carboxypeptidase A1 (pancreatic), CPA
+ [2]
Introduction
Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro (PubMed:20385563, PubMed:8806703). Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond (By similarity).

Related

1
Drugs associated with CPA1
CN118652909
Patent Mining
Target
CPA1
Mechanism-
Active Org.
China Veterinary Drug Administration
Originator Org.
China Veterinary Drug Administration
Active Indication
Hemic and Lymphatic Diseases [+1]
Inactive Indication-
Drug Highest PhaseDiscovery
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
100 Clinical Results associated with CPA1
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100 Translational Medicine associated with CPA1
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0 Patents (Medical) associated with CPA1
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1,461
Literatures (Medical) associated with CPA1
01 Jun 2025Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
Knockdown of cytochrome P450 1 A (cyp1a) gene suppresses growth and oxygen tolerance in zebrafish
23 Apr 2025Chemical Reviews
Controlling Stereoselectivity with Noncovalent Interactions in Chiral Phosphoric Acid Organocatalysis
01 Apr 2025Gut
AlphaMissense versus laboratory-based pathogenicity prediction of 13 novel missenseCPA1variants from pancreatitis cases

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