Last update 23 Jan 2025

SERT x 5-HT1D receptor x σ1 receptor x 5-HT2C receptor x 5-HT2A receptor

Basic Info

Related Targets
SERT5-HT1D receptorσ1 receptor[+2]

Related

1
Drugs associated with SERT x 5-HT1D receptor x σ1 receptor x 5-HT2C receptor x 5-HT2A receptor
Fenfluramine Hydrochloride
Target
5-HT1D receptor x 5-HT2A receptor x 5-HT2C receptor x SERT x σ1 receptor
Mechanism
5-HT1D receptor agonists [+4]
Active Org.
Zogenix, Inc.Zogenix, Inc. [+6]
Originator Org.
Zogenix, Inc.Zogenix, Inc.
Active Indication
Lennox Gastaut Syndrome [+7]
Inactive Indication
Drug Resistant Epilepsy
Drug Highest PhaseApproved
First Approval Ctry. / Loc.
US
First Approval Date25 Jun 2020
31
Clinical Trials associated with SERT x 5-HT1D receptor x σ1 receptor x 5-HT2C receptor x 5-HT2A receptor
NCT06679413
/ RecruitingPhase 1
A Phase 1, Single-Center, Repeat-Dose, Open-Label, Fixed-Sequence Drug-Drug Interaction Study of ZX008 in Healthy Male Or Female Study Participants 18 To 55 Years Of Age
100 Clinical Results associated with SERT x 5-HT1D receptor x σ1 receptor x 5-HT2C receptor x 5-HT2A receptor
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100 Translational Medicine associated with SERT x 5-HT1D receptor x σ1 receptor x 5-HT2C receptor x 5-HT2A receptor
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0 Patents (Medical) associated with SERT x 5-HT1D receptor x σ1 receptor x 5-HT2C receptor x 5-HT2A receptor
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