Last update 08 May 2025

PDE3A x DHODH

Basic Info

Related Targets
PDE3ADHODH

Related

1
Drugs associated with PDE3A x DHODH
Brequinar Sodium
Target
DHODH x PDE3A
Mechanism
DHODH inhibitors [+1]
Active Org.
First Affiliated Hospital of Xi'an Jiaotong University
Originator Org.
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Active Indication
Estrogen receptor positive breast cancer
Inactive Indication
COVID-19 [+4]
Drug Highest PhasePreclinical
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
5
Clinical Trials associated with PDE3A x DHODH
NCT05166876
/ TerminatedPhase 2
A Phase II, Randomized, Assessor-blind, Multicenter, Multi-dose, Placebo-controlled Study Assessing the Safety and Anti-coronavirus Response of Brequinar Combined With Dipyridamole in Patients With Mild to Moderate SARS-CoV-2 Infection.
CTRI/2021/12/038651
/ RecruitingPhase 2
A phase II, randomized, assessor-blind, multicenter, multi-dose, placebo-controlled study assessing the safety and anti-coronavirus response of brequinar combined with dipyridamole in patients with mild to moderate SARS-CoV-2 infection.
100 Clinical Results associated with PDE3A x DHODH
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100 Translational Medicine associated with PDE3A x DHODH
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0 Patents (Medical) associated with PDE3A x DHODH
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