What are the side effects of Crisaborole?

Crisaborole, marketed under the brand name Eucrisa, is a topical ointment used primarily for the treatment of mild to moderate atopic dermatitis (eczema). While it has been proven effective in alleviating the symptoms of eczema, it is also important to be aware of potential side effects that could arise during its use. Here, we will delve into the common and less common side effects associated with Crisaborole, as well as some considerations you should keep in mind.

One of the most commonly reported side effects of Crisaborole is application site reactions. These can include symptoms such as burning, stinging, pain, or itching at the site where the ointment is applied. These reactions are generally mild to moderate and tend to diminish as the skin adjusts to the treatment over time. However, if they persist or become too uncomfortable, it is advisable to consult with a healthcare professional.

Another side effect that can occur, although less frequently, is hypersensitivity. Hypersensitivity reactions may involve the development of contact dermatitis, which manifests as redness, swelling, and itching at the site of application. In rare cases, more severe allergic reactions can occur, leading to symptoms like hives, swelling of the face, lips, tongue, or throat, and difficulty breathing. These severe reactions require immediate medical attention and discontinuation of the ointment.

In addition to the localized effects, there are some systemic side effects that could potentially occur, although they are rare. These may include headache, nausea, or dizziness. If you experience any of these symptoms, it is important to discuss them with your healthcare provider to determine whether Crisaborole is the right treatment for you.

It's also worth noting that while Crisaborole is generally well-tolerated in most patients, certain populations should exercise caution. For instance, the safety and effectiveness of Crisaborole in children under two years of age have not been established, and thus it is not recommended for use in this age group. Pregnant and breastfeeding women should also consult their healthcare providers before starting treatment, as there is limited data on the safety of Crisaborole in these populations.

Moreover, individuals with a history of sensitivity to any of the components of the ointment should avoid using Crisaborole to prevent adverse reactions. It's always a good practice to review the ingredient list and discuss any known allergies with your healthcare provider.

In conclusion, while Crisaborole is an effective treatment for atopic dermatitis, it is not without its side effects. Common side effects include application site reactions like burning and itching, while less common but serious side effects can involve hypersensitivity and systemic reactions. Always consult with your healthcare provider to ensure that Crisaborole is a safe and suitable option for your specific condition, and report any adverse effects you experience during its use. This will help you manage your eczema effectively while minimizing potential risks.