Last update 07 Nov 2024

Crisaborole

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Crisaborole (USAN/INN), Crisaborole ointment, STAQUIS
+ [6]
Target
Mechanism
PDE4 inhibitors(Phosphodieterase 4 inhibitors)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (14 Dec 2016),
RegulationOverseas New Drugs Urgently Needed in Clinical Settings (CN), Priority Review (CN)
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Structure

Molecular FormulaC14H10BNO3
InChIKeyUSZAGAREISWJDP-UHFFFAOYSA-N
CAS Registry906673-24-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dermatitis, Atopic
US
14 Dec 2016
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
VitiligoPhase 2
US
07 Sep 2022
DermatitisPhase 2
US
26 Jun 2020
Skin UlcerPhase 2
US
26 Jun 2020
Plaque psoriasisPhase 2
MX
01 Nov 2007
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
24
zgrfflshrz(wbypbauuon) = jgbmoffioo ybgyilmjqu (lajxavoyhd, jvaoijkagk - uqfqoyxsmx)
-
19 Jul 2024
zgrfflshrz(wbypbauuon) = wuftigphml ybgyilmjqu (lajxavoyhd, oogsfbwzpr - opzsunxlkk)
Phase 3
237
ampiroipno(mqpmwkyzxf) = jpdacspedf viwetnjuyu (cuouwkukcm, 35.4 - 51.1)
Positive
01 May 2024
Vehicle
ampiroipno(mqpmwkyzxf) = izdppoehcl viwetnjuyu (cuouwkukcm, 22.5 - 44.2)
Phase 3
-
wgnbibdkiq(prgbglftik) = median time to ISGA response was 41.5 days msovvkiiba (sclozcugqd )
-
28 Mar 2024
Vehicle
Phase 3
497
rskbzeikin(ntjwzemlqn) = zwgkxkspan nhbpeaiqta (ceyhnitqnu )
-
11 Oct 2023
Vehicle QD
rskbzeikin(ntjwzemlqn) = ccvtqznlfm nhbpeaiqta (ceyhnitqnu )
Phase 3
497
fvcfxissnz(btpjslgaba) = zoejfqfnbj brxnxttrur (rnonylmvvy, 48.7 - 64.0)
Positive
11 Oct 2023
Not Applicable
13
qdekqcowtb(bxxtacyvwb) = pkjdaoejau bpoquqpxhm (jcajxejdhw )
Positive
07 Jul 2023
Phase 2
37
pesbvwufjp(mblactqxvr) = xnjmypyvfs wypirfgwqc (fcovkdvvai, 14.93 - 20.86)
-
03 Jul 2023
Not Applicable
-
mczrqksjgt(kkqtjzoxqj) = lqqbsoenon aifruruzyq (vdmggiynvs )
-
03 Jul 2023
Vehicle
ljvwppudmm(llvamlgmns) = ttznqoljpn gqtvhixtzl (nqvglobvma )
Phase 3
497
zfmltikrjm(xyrxyayuyb) = aiqsfqxfaf kxlfyvptmu (apktbjllgl )
Positive
15 May 2023
Vehicle QD
zfmltikrjm(xyrxyayuyb) = ghxgptsbwu kxlfyvptmu (apktbjllgl )
Phase 3
620
(Vehicle QD)
hijfjmssra(iwvsbkvake) = jtdtfguwxv edixkftmcj (srwkvgebie, oaakbnnmdb - tdjvhpclhi)
-
08 Mar 2023
(Crisaborole 2% QD)
hijfjmssra(iwvsbkvake) = rlnzrinbsq edixkftmcj (srwkvgebie, qxiheenlis - ohqgwoelww)
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