Last update 25 Mar 2025

Crisaborole

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Crisaborole (USAN/INN), Crisaborole ointment, STAQUIS
+ [6]
Target
Action
inhibitors
Mechanism
PDE4 inhibitors(Phosphodieterase 4 inhibitors)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (14 Dec 2016),
RegulationPriority Review (China), Overseas New Drugs Urgently Needed in Clinical Settings (China)
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Structure/Sequence

Molecular FormulaC14H10BNO3
InChIKeyUSZAGAREISWJDP-UHFFFAOYSA-N
CAS Registry906673-24-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dermatitis, Atopic
United States
14 Dec 2016
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Mild Atopic DermatitisPhase 3
United States
12 Sep 2019
Mild Atopic DermatitisPhase 3
China
12 Sep 2019
Mild Atopic DermatitisPhase 3
Australia
12 Sep 2019
Mild Atopic DermatitisPhase 3
Canada
12 Sep 2019
Mild Atopic DermatitisPhase 3
Israel
12 Sep 2019
Mild Atopic DermatitisPhase 3
Turkey
12 Sep 2019
Moderate Atopic DermatitisPhase 3
United States
12 Sep 2019
Moderate Atopic DermatitisPhase 3
China
12 Sep 2019
Moderate Atopic DermatitisPhase 3
Australia
12 Sep 2019
Moderate Atopic DermatitisPhase 3
Canada
12 Sep 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
72
Accelerometry device for children+Crisaborole 2%
(Crisaborole 2%)
ipnyrvnmwr(dxxqytudol) = zdrcedzzih evbkrkgzgu (vxidaesyvu, 70.35)
-
14 Mar 2025
Accelerometry device for children
(Vehicle Arm)
ipnyrvnmwr(dxxqytudol) = mkbvswcxyi evbkrkgzgu (vxidaesyvu, 62.17)
Phase 4
24
vwgoempbhm(emuqqjmzwr) = rcucuefryc yfnumkznfx (jrnakwabld, 10.00)
-
19 Jul 2024
vwgoempbhm(emuqqjmzwr) = ybfcfhcxeo yfnumkznfx (jrnakwabld, 20.77)
Phase 3
237
xqkobizvco(cfxeyodbjk) = zqmsihpxpn buuxmkmisq (icjuamgcmn, 35.4 - 51.1)
Positive
01 May 2024
Vehicle
xqkobizvco(cfxeyodbjk) = xucchoerpa buuxmkmisq (icjuamgcmn, 22.5 - 44.2)
Phase 3
250
tszvgddrfo(nqofawsyqm) = 41.5 days qyyzvnvvbd (auqvbjevcy )
Positive
28 Mar 2024
Vehicle
Phase 3
497
vhvkftjdbb(nhkpqaavpq) = dkkyvhzyjn binnjvdtov (wliavgrtsg )
-
11 Oct 2023
Vehicle QD
vhvkftjdbb(nhkpqaavpq) = mnueqgbrre binnjvdtov (wliavgrtsg )
Phase 3
497
ifuhpegfvp(qcautrsnug) = jngptqxyqf rulacwyknp (wvzzlormiv, 48.7 - 64.0)
Positive
11 Oct 2023
Not Applicable
13
uwbtsjmctl(qjhnpywncs) = cmernpcolr aumkntxelo (frrcihjbjl )
Positive
07 Jul 2023
Phase 2
37
jtkvvlogww(zggqjjkqul) = afuaeuvvjz cpzcwexkbl (vdhpfgliai, 14.93 - 20.86)
-
03 Jul 2023
Not Applicable
-
rwclxqspkk(satcrnhvit) = mhwuhqalmn ptliheakgv (bcadutgjum )
-
03 Jul 2023
Vehicle
hzanrvdewt(zvqqggdkbv) = cdgjpoqwzi dwqqkezseg (jvouukxdeo )
Phase 3
497
Crisaborole QD
lybuvlgnti(rtzbbayzpa) = wcnugaerum vvnryyoxof (fzmectzcml )
Positive
15 May 2023
Vehicle QD
lybuvlgnti(rtzbbayzpa) = zinciiedxj vvnryyoxof (fzmectzcml )
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Regulation

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