What are the side effects of Diquafosol Sodium?

Diquafosol Sodium is a medication primarily used to treat dry eye disease, a condition that can cause significant discomfort and impair quality of life. It works by stimulating the secretion of mucin and water from the conjunctival epithelium, thereby promoting an increase in tear production and improving the overall stability of the tear film.

While Diquafosol Sodium is generally well-tolerated, like any medication, it can have side effects. Understanding these potential side effects is crucial for patients and healthcare providers to manage and mitigate any adverse reactions effectively.

One of the most commonly reported side effects of Diquafosol Sodium is eye irritation. Patients may experience a burning or stinging sensation upon instillation of the eye drops. This sensation is usually temporary and tends to diminish as the eyes become accustomed to the medication. However, if the irritation persists, it is advisable to consult a healthcare professional.

Another frequent side effect is temporary blurred vision. This can occur immediately after applying the eye drops and typically resolves after a few minutes. Patients are generally advised to avoid activities that require clear vision, such as driving or operating heavy machinery, until their vision returns to normal.

Redness of the eyes is another potential side effect. This redness, also known as conjunctival hyperemia, is usually mild and transient. However, if the redness is severe or prolonged, it may indicate an allergic reaction or other underlying issues that require medical attention.

Some patients may also experience a foreign body sensation in the eyes, where it feels as though there is something in the eye. This can be uncomfortable but is typically temporary. If this sensation persists or worsens, it is important to seek medical advice, as it may be a sign of an adverse reaction to the medication.

Less commonly, patients might experience eyelid inflammation, known as blepharitis. Symptoms of blepharitis include swelling, redness, and itching of the eyelids. Proper eyelid hygiene and the use of prescribed medications can help manage this condition effectively.

Another rare side effect is corneal disorders, including superficial punctate keratitis, which involves tiny, superficial damage to the cornea. Symptoms may include discomfort, redness, and sensitivity to light. If such symptoms occur, it is crucial to seek immediate medical attention to prevent potential complications.

Allergic reactions to Diquafosol Sodium are rare but possible. Symptoms of an allergic reaction may include itching, swelling, and severe redness of the eyes, as well as difficulty breathing in severe cases. If any of these symptoms occur, it is imperative to discontinue the use of the medication and seek urgent medical care.

In conclusion, while Diquafosol Sodium is effective in managing dry eye disease, it is essential for patients to be aware of its potential side effects. Most side effects are mild and temporary, but some may require medical attention. Patients should always follow their healthcare provider's instructions and report any persistent or severe side effects to ensure safe and effective use of the medication.