What are the side effects of Ketorolac Tromethamine?

Ketorolac Tromethamine is a potent nonsteroidal anti-inflammatory drug (NSAID) used for the short-term treatment of moderate to severe pain. While effective, it is crucial to be aware of its potential side effects, which can range from mild to severe. Understanding these side effects can help manage expectations and ensure proper use.

One of the most common side effects of Ketorolac Tromethamine is gastrointestinal discomfort. This can manifest as stomach pain, indigestion, nausea, and vomiting. It may also cause more severe gastrointestinal issues such as ulcers or gastrointestinal bleeding, which are more likely with prolonged use or higher doses. Symptoms of gastrointestinal bleeding include black or bloody stools, and vomiting that looks like coffee grounds.

Renal problems are another possible side effect. Ketorolac Tromethamine can affect kidney function, leading to conditions such as fluid retention, decreased urination, and kidney failure. These risks are elevated in patients with pre-existing kidney conditions or those taking certain medications concurrently.

Cardiovascular side effects can also occur and include increased blood pressure, heart palpitations, and in some cases, severe conditions like heart attack or stroke. These risks are generally higher in individuals with a history of heart disease or hypertension.

The drug can also cause allergic reactions. Symptoms can range from mild rashes and itching to severe reactions like anaphylaxis, which require immediate medical attention. Signs of a severe allergic reaction include difficulty breathing, swelling of the face or throat, and hives.

Hematologic issues such as anemia and prolonged bleeding times have also been linked to Ketorolac Tromethamine use. This is particularly crucial for patients scheduled for surgery or those with clotting disorders.

Ketorolac Tromethamine can also affect the liver, causing elevated liver enzymes, which may indicate liver damage. Symptoms to watch for include yellowing of the skin or eyes (jaundice), dark urine, and severe fatigue.

Neurological side effects such as headaches, dizziness, and drowsiness are relatively common. In rare cases, it can cause more severe conditions like seizures or aseptic meningitis, especially in patients with autoimmune disorders like lupus.

Finally, respiratory side effects such as shortness of breath and bronchospasm can occur, particularly in individuals with asthma or other chronic respiratory conditions.

In summary, while Ketorolac Tromethamine is effective for pain relief, it comes with a range of potential side effects that can impact various bodily systems. It is essential to use this medication under medical supervision, especially if there are pre-existing health conditions or concurrent medication use. Always consult healthcare providers for a complete understanding of the risks and to ensure safe usage.