What are the side effects of Mavacamten?

Mavacamten is a medication that has garnered significant attention in recent times for its potential benefits in treating hypertrophic cardiomyopathy (HCM), a condition characterized by the thickening of the heart muscle. While its therapeutic effects are promising, understanding the side effects associated with Mavacamten is crucial for both patients and healthcare providers.

One of the most common side effects reported with Mavacamten use is dizziness. This can be particularly concerning for individuals who operate heavy machinery or drive, as dizziness can impair their ability to perform these tasks safely. Patients experiencing persistent dizziness should consult their healthcare provider to adjust their dosage or explore alternative treatments.

Another side effect that has been observed is fatigue. Fatigue can significantly impact daily activities and overall quality of life. It is essential for patients to monitor their energy levels and report any extreme or prolonged fatigue to their healthcare provider. This side effect may necessitate a reevaluation of the treatment plan to ensure the patient’s well-being.

Shortness of breath is also a reported side effect of Mavacamten. Although it is often associated with the underlying condition of HCM, any new or worsening shortness of breath should be evaluated by a healthcare provider. This symptom could indicate an adverse reaction to the medication or a progression of the disease.

Additionally, some patients have reported experiencing low blood pressure (hypotension) while on Mavacamten. Symptoms of hypotension can include lightheadedness, fainting, and blurred vision. It is important for patients to monitor their blood pressure regularly and discuss any significant changes with their healthcare provider.

In rare cases, Mavacamten can cause an increase in liver enzymes, which may indicate liver stress or damage. Routine blood tests are typically conducted to monitor liver function in patients taking Mavacamten. Any significant changes in liver enzyme levels may require discontinuation of the medication to prevent further liver complications.

Another serious but less common side effect is cardiac arrhythmias, or irregular heartbeats. Patients may experience palpitations, or the sensation of their heart skipping a beat. This side effect requires immediate medical attention, as arrhythmias can pose significant risks to heart health.

Furthermore, patients should be aware of potential allergic reactions to Mavacamten. Symptoms of an allergic reaction can include rash, itching, swelling, severe dizziness, and difficulty breathing. Any signs of an allergic reaction warrant immediate medical intervention.

In conclusion, while Mavacamten holds promise for treating hypertrophic cardiomyopathy, it is essential to be aware of its potential side effects. Dizziness, fatigue, shortness of breath, low blood pressure, increased liver enzymes, cardiac arrhythmias, and allergic reactions are among the possible adverse effects. Patients taking Mavacamten should maintain regular consultations with their healthcare provider to monitor their condition and ensure that any side effects are managed promptly and effectively.