A Complete Guide to Searching Diphenhydramine on Synapse

Diphenhydramine (DPH) is an antihistamine and sedative mainly used to treat allergies, insomnia, and symptoms of the common cold. It is taken by mouth, injected into a vein, injected into a muscle, or applied to the skin. Maximal effect is typically around two hours after a dose, and effects can last for up to seven hours. It is a first generation H1-antihistamine and ethanolamine and works by blocking certain effects of histamine, which produces its antihistamine and sedative effects. Diphenhydramine is also a potent anticholinergic. Common side effects include sleepiness, poor coordination and an upset stomach. Click on the image below to begin the exploration journey of Diphenhydramine through the Synapse database!

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