Recent blog posts
Bio-Thera Launches BAT6026 OX40 Targeted Monoclonal Antibody Phase IB/IIA Clinical Trial for Moderate to Severe Atopic Dermatitis Patients
Pharma Pioneer
2 min read
Bio-Thera Launches BAT6026 OX40 Targeted Monoclonal Antibody Phase IB/IIA Clinical Trial for Moderate to Severe Atopic Dermatitis Patients
31 May 2024
Bio-Thera Solutions has initiated a Phase IA/IIA clinical trial for BAT6026, a monoclonal antibody designed to target OX40.
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FDA Approves Theradaptive's IDE for Phase I/II Spinal Fusion Trials
Pharma Pioneer
3 min read
FDA Approves Theradaptive's IDE for Phase I/II Spinal Fusion Trials
31 May 2024
Therapeutic company Theradaptive has received approval from the U.S. FDA to initiate a global Phase I/II study for its spinal fusion product, OsteoAdapt SP.
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Sirius Launches Phase 1 Trial for Innovative FXI siRNA Anticoagulant in Thromboembolic Treatment
Pharma Pioneer
2 min read
Sirius Launches Phase 1 Trial for Innovative FXI siRNA Anticoagulant in Thromboembolic Treatment
31 May 2024
Sirius Therapeutics has initiated a Phase 1 clinical trial for SRSD107, an innovative siRNA treatment aimed at preventing and managing thromboembolic disorders by targeting coagulation Factor XI (FXI).
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Tharimmune Initiates Phase 1 Trial with TH104 for Treating Itch in Primary Biliary Cholangitis
Pharma Pioneer
2 min read
Tharimmune Initiates Phase 1 Trial with TH104 for Treating Itch in Primary Biliary Cholangitis
31 May 2024
The first individual has been administered TH104 in a Phase 1 clinical trial, focusing on the drug's safety, tolerability, and absolute bioavailability.
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Sangamo Presents Positive Phase 1/2 Gene Therapy Data for Fabry Disease
Pharma Pioneer
2 min read
Sangamo Presents Positive Phase 1/2 Gene Therapy Data for Fabry Disease
31 May 2024
Sangamo Therapeutics has reported positive interim results from its Phase 1/2 STAAR clinical trial for isaralgagene civaparvovec (ST-920), a gene therapy for Fabry disease.
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ProLynx Launches Phase I/II Trial of DNA-Damaging PLX038 for Rare CNS Tumors at NCI
Pharma Pioneer
3 min read
ProLynx Launches Phase I/II Trial of DNA-Damaging PLX038 for Rare CNS Tumors at NCI
31 May 2024
ProLynx Inc. initiated a Phase I/II clinical study involving PLX038, a PEGylated form of SN-38, for treating primary central nervous system (CNS) tumors with MYC or MYCN gene amplifications.
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ProfoundBio Initiates Phase 1/2 Trial for PTK7-Targeted ADC PRO1107
Pharma Pioneer
2 min read
ProfoundBio Initiates Phase 1/2 Trial for PTK7-Targeted ADC PRO1107
31 May 2024
ProfoundBio has launched the Phase 1/2 clinical trial for PRO1107, marking a significant step in their mission to enhance patient outcomes.
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Rani Therapeutics Reports Positive Phase 1 Results for Oral Anti-IL 12/23 Antibody (RT-111)
Pharma Pioneer
2 min read
Rani Therapeutics Reports Positive Phase 1 Results for Oral Anti-IL 12/23 Antibody (RT-111)
31 May 2024
Rani Therapeutics Holdings, Inc. reported encouraging topline results from its Phase 1 clinical trial of RT-111, a RaniPill® capsule containing an ustekinumab biosimilar (CT-P43).
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Triumvira Begins Phase I/II Trial for TAC101-CLDN18.2 Solid Tumor Therapy
Pharma Pioneer
3 min read
Triumvira Begins Phase I/II Trial for TAC101-CLDN18.2 Solid Tumor Therapy
31 May 2024
This study is focused on evaluating the safety and effectiveness of TAC101-CLDN18.2, an advanced cell therapy that utilizes genetically modified autologous T cells.
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Neuroinflammation: Alzheimer's Promising Treatment Target
Pharma Pioneer
3 min read
Neuroinflammation: Alzheimer's Promising Treatment Target
31 May 2024
In the early 20th century, Alois Alzheimer identified neuroinflammation as a factor in the disease now named after him, noting the presence of microglia cells in his initial sketches.
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Upcoming Alzheimer's Treatments: 5 Key Data Results in 2024
Pharma Pioneer
2 min read
Upcoming Alzheimer's Treatments: 5 Key Data Results in 2024
29 May 2024
Recent advancements in Alzheimer's treatment are promising, with Biogen and Eisai's Leqembi receiving full approval in July, and EliLilly's donanemab potentially following suit soon.
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MariTide: Amgen's Experimental Obesity Drug Demonstrates Sustained Weight Loss in Phase I
Pharma Pioneer
2 min read
MariTide: Amgen's Experimental Obesity Drug Demonstrates Sustained Weight Loss in Phase I
29 May 2024
Phase I clinical trial results for Amgen’s experimental weight-loss drug, MariTide, indicate it may provide longer-lasting effects compared to existing glucagon-like peptide-1 (GLP-1) treatments such as Novo Nordisk’s Wegovy and EliLilly’s Zepbound.
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