Achilles Therapeutics plc has reported interim Phase I/IIa clinical trial data for clonal neoantigen reactive T cells (cNeT) from the CHIRON study for non-small cell lung cancer (NSCLC) and the THETIS study for malignant melanoma
This innovative vaccine, developed by CureVac, is multivalent and contains antigens that match the four flu strains recommended by the World Health Organization (WHO).
Eilean Therapeutics LLC has received approval from the Human Research Ethics Committee in Australia to commence a Phase I clinical trial for lomonitinib (ZE46-0134).
TPST-1120, a novel oral PPAR⍺ inhibitor, has shown promising results in treating cancers that are resistant to PD-1 inhibitors and those with weakened immune systems.
LOTIS-7 Phase 1b Trial Completes Dose Escalation: ZYNLONTA® and Bispecific Antibodies for Non-Hodgkin Lymphoma Patients, No Severe Side Effects Observed.
Ocugen, Inc. has received approval from the Data and Safety Monitoring Board (DSMB) to advance to the medium dose cohort in the Phase 1/2 clinical trial for OCU410.
Geneos Therapeutics has reported successful results from its GT-30 clinical trial, showcasing the safety and effectiveness of a personalized therapeutic cancer vaccine (PTCV) for patients with advanced hepatocellular carcinoma (HCC).
The three-year outcomes from a Phase 1 study of a personalized mRNA cancer vaccine, autogene cevumeran (BNT122, RO7198457), have demonstrated sustained polyspecific T cell reactions and a reduction in tumor recurrence in patients.