Effortless Searching: How to Find Nifedipine on Synapse

Nifedipine is a small molecule drug that acts as a blocker of voltage-dependent calcium channels (VDCCs), which are involved in the regulation of calcium ions in the cardiovascular system. By inhibiting these channels, nifedipine reduces calcium influx into smooth muscle cells, leading to vasodilation and a decrease in blood pressure. This drug is primarily used to treat hypertension, including renovascular and essential hypertension, as well as angina pectoris and other cardiovascular diseases. Nifedipine was first developed and marketed by Bayer AG, and received its first approval in 1975. Since then, it has become a widely used medication for the management of hypertension and related conditions, although its use is associated with potential adverse effects such as hypotension, dizziness, and headache. As such, it should be used with caution and under the supervision of a healthcare professional. Click on the image below to begin the exploration journey of Nifedipine through the Synapse database!

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